Results 61 to 70 of about 2,058,475 (281)

Octonion-based transform moments for innovative stereo image classification with deep learning

open access: yesComplex & Intelligent Systems
Recent advances in imaging technologies have led to a significant increase in the adoption of stereoscopic images. However, despite this proliferation, in-depth research into the complex analysis of the visual content of these stereoscopic images is ...
Mohamed Amine Tahiri   +9 more
doaj   +1 more source

The Lisbon moment : challenges and innovations for EU diplomacy [PDF]

open access: yes, 2013
The increasing complexity, interdependence and acceleration of global developments, digital media and the growing share of global public goods, have all contributed to the publicitisation, sectoralisation and summitization of foreign policy worldwide.
Gerhard Sabathil, Wenwen Shen
openaire   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Innovative Moments and Change in Emotion-Focused Therapy: The Case of Lisa [PDF]

open access: yesJournal of Constructivist Psychology, 2010
This article presents an intensive analysis of a good-outcome case of emotion-focused therapy—the case of Lisa—using the Innovative Moments Coding System (IMCS). IMCS, influenced by narrative therapy, conceptualizes narrative change as resulting from the elaboration and expansion of narrative exceptions or unique outcomes to a client's core problematic
Gonçalves, Miguel M.   +4 more
openaire   +3 more sources

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

COMPLETE MOMENT CONVERGENCE OF MOVING AVERAGE PROCESSES WITH DEPENDENT INNOVATIONS [PDF]

open access: yesJournal of the Korean Mathematical Society, 2008
The result of Li and Zhang is extended to the sequence \(\{Y_i ...
Kim, Tae-Sung   +2 more
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Drawing on the Innovative Moments Model during Career Construction Counseling to explain and foster client change [PDF]

open access: yes, 2019
Career Construction Counseling (CCC) is a narrative intervention that supports individuals in the elaboration of narrative identity and career construction.
Cardoso, Paulo   +2 more
core   +1 more source

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