AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Immersive Composition for Sensory Rehabilitation: 3D Visualisation, Surround Sound, and Synthesised Music to Provoke Catharsis and Healing [PDF]
There is a wide range of sensory therapies using sound, music and visual stimuli. Some focus on soothing or distracting stimuli such as natural sounds or classical music as analgesic, while other approaches emphasize the active performance of producing ...
A. Cohen +9 more
core +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
DRIVING IN EMERGENCIES WITH USE OF SYSTEM OF THE HELP TO THE DRIVER
The purpose of this article consists in research of modern technologies in automotive industry by the analysis and carrying out technical experiment. The main attention concentrates on traffic safety, which is carried out by automation and modernization ...
Svetlana Alekseevna Vasyugova +1 more
doaj +1 more source
Living lab approach for developing massmarket IoT products and services [PDF]
Internet of Things (IoT) has emerged as a central concept in both the industrial as in the academic world. In this context, Living Lab research has been shown as an effective means for the design, implementation, development, testing and validation of ...
Schuurman, Dimitri, Vandenbroucke, Karel
core
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
AESHML: An Automatic Editing Method for Soccer Match Highlights Using Multimodal Learning
With the increasing prevalence of short videos, viewers are increasingly seeking concise and engaging segments of video content. In soccer matches, despite the fact that the duration of the match often exceeds 90 minutes, it is the brief highlight ...
Mengjiao Han, Peng Wen, Jie Zhao
doaj +1 more source
Exploring an innovative approach to study browsing behavior of dairy cows and the performance of self-mecative behavior in relation browsing [PDF]
N/
Roelen, S.S.M.
core
Three narrative-based coding systems: innovative moments, ambivalence and ambivalence resolution [PDF]
Narrative and dialogical perspectives suggest that personal meaning systems’ flexibility is an important resource for change in psychotherapy. Drawn from these theoretical backgrounds, a research program focused on the identification of Innovative ...
Alves, Diana +9 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source

