Results 81 to 90 of about 997,334 (306)

Ethical hurdles in the prioritization of oncology care [PDF]

, 2016
With finite resources, healthcare payers must make difficult choices regarding spending and the ethical distribution of funds. Here, we describe some of the ethical issues surrounding inequity in healthcare in nine major European countries, using cancer ...
Capri, Stefano, Castanier, Jean-Claude, Cunningham, David, de Groot, Folkert, Flamion, Bruno, Flume, Mathias, Herholz, Harald, Levin, Lars-Åke, Rupprecht, Christoph J., Shalet, Natalie, Solà-Morales, Oriol, Walker, Andrew, Wong, Olivier   +12 more
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Disaster Resilience Education and Research Roadmap for Europe 2030 : ANDROID Report [PDF]

, 2015
A disaster resilience education and research roadmap for Europe 2030 has been launched. This roadmap represents an important output of the ANDROID disaster resilience network, bringing together existing literature in the field, as well as the results of ...
Amaratunga, Dilanthi, Faber, M., Haigh, Richard, Indirli, M., Kaklauskas, Arturas, Lill, I., Perdikou, S., Perera, S., Rochas, C., Sparf, J., Thayaparan, Menaha, Velazquez, J.   +11 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Perception of undergraduate medical students regarding “Reel-Making” as an innovative learning method in ophthalmology: a cross-sectional study

BMC Medical Education
Background The perceptions and learning methods among students have been rapidly changing over the past few years, and thus, there is a need for innovative teaching-learning methods to train the Indian Medical Graduates in the present day. Objectives The
Sunayana Bhat, Madhurima A. Nayak, Vinay PG   +2 more
doaj   +1 more source

Quantifying Changes in Creativity: Findings from an Engineering Course on the Design of Complex and Origami Structures [PDF]

, 2018
Engineering educators have increasingly sought strategies for integrating the arts into their curricula. The primary objective of this integration varies, but one common objective is to improve students’ creative thinking skills. In this paper, we sought
Anwar, Sohel, Fore, Grant, Hess, Justin L., Rao, Anusha Sathyanarayanan, Tovar, Andres, Wu, Jiangmei   +5 more
core  

Innovation Indicators: for a critical reflection on their use in Low- and Middle-Income Countries (LMICs) [PDF]

, 2020
It has been widely recognized that innovation is an important driver of economic growth. Many Low- and Middle-Income Countries (LMICs) have adopted innovation indicators to monitor innovation performance and to evaluate the impact of innovation policies.
HOLLANDERS Hugo, IIZUKA Michiko, UNU-MERIT, 政策研究大学院大学 / National Graduate Institute for Policy Studies   +3 more
core   +1 more source

Internet Surveys by Direct Mailing: An Innovative Way of Collecting Data [PDF]

, 1997
This article describes a new method of collecting data by direct mailing via the Internet. Feasibility and capacities were evaluated through a worldwide opinion poll on global future risks of mankind and potential solutions.
Dillman, D.A., Frey, J.H., Nikolai Mühlberger, Rolf Weitkunat, Sebastian Schneeweiß, The Internet Society., Walter J. Swoboda   +6 more
core   +1 more source

A Comprehensive Survey on Split-Fed Learning: Methods, Innovations, and Future Directions

IEEE Access
In this work we presented Split-Fed Learning (SFL), a new framework that combines the concepts of Federated Learning (FL) and Split Learning (SL), to provide privacy-aware and scalable training of machine learning models in settings with distributed data.
Geetabai S. Hukkeri, R. H. Goudar, G. M. Dhananjaya, Vijayalaxmi N. Rathod, Shilpa Ankalaki   +4 more
openaire   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source