Results 81 to 90 of about 2,637,941 (347)

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Prospects for the application of active learning methods in modern education

open access: yesPolítica e Gestão Educacional, 2021
The article examines the prospects for the application of active learning methods in modern education. The survey shows that the prospects for the application of active learning methods in modern education are conditioned by the influence of different ...
Tunzala Verdiyeva
doaj   +1 more source

Survey on Principles of e-Regulation project [PDF]

open access: yes, 2010
"There is an increasing use of technology for the development, delivery, administration and reporting of assessment in qualifications offered by AOs. The UK qualifications regulators published Regulatory Principles for e-Assessment in April 2007.

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Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Human Resource Management Diffusion and Productivity Imbalances [PDF]

open access: yes, 2019
In this study, we explore spatial variance in management practices and assess its potential contribution to regional imbalances in productivity. The research builds on a growing body of evidence which indicates that differences in management practices ...
Askenazy, P., Bryson, A., Forth, J.
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Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Innovative Improvement in the Physical Education Learning Experience: A Study at Dela Paz National High School Philippines

open access: yesPhysical Activity Journal
This study aims to investigate the impact of innovative teaching approaches, specifically learning and the utilization of technology, on students' academic performance and their development of critical thinking skills, leadership skills, social skills ...
Jomar Seguro Tianio   +1 more
doaj   +1 more source

The Use and Teaching of Agile Software Development in the Czech Republic

open access: yesActa Informatica Pragensia, 2020
Digital transformation requires usage of effective software development methods, techniques, and tools for innovative IT solutions development. Agile methods, that are broadly adopted in recent years, fulfil this role.
Alena Buchalcevová
doaj   +1 more source

Innovation modes and productivity in the UK [PDF]

open access: yes, 2008
This paper is motivated by the aim to develop appropriate indicators capturing modes of innovation by UK enterprises, examine how such innovation practices vary across regions and industries and explore the extent to which they have an impact on ...
Frenz, Marion, Lambert, Ray
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