NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang +10 more
wiley +1 more source
Soil microbial community differences drive variation in Pinus sylvestris physiology, productivity, and responses to elevated CO<sub>2</sub>. [PDF]
Anthony MA +16 more
europepmc +1 more source
De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li +23 more
wiley +1 more source
Assessment of quality and rumen degradability of mixed silages of sugarcane tops with Marabú forage [PDF]
Arce González, Miguel Ángel +4 more
core
Determining the optimal inoculant rate to maximize soybean productivity in the Guinea Savanna agro-ecological zone of Ghana. [PDF]
Abdul-Aziz AL +7 more
europepmc +1 more source
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao +11 more
wiley +1 more source
Dose-optimized microbial inoculants reshape grape rhizosphere microbiota and enhance fruit quality. [PDF]
Chang X +10 more
europepmc +1 more source
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun +5 more
wiley +1 more source
Innate defense mechanisms against Nosema ceranae in hygienic honey bee (Apis mellifera) colonies. [PDF]
Miller MS +6 more
europepmc +1 more source

