Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Experiences with Small-Flaking or Granular Agglutination in Normal, Inoculated and Enteric Fever Cases [PDF]
John C. Wyllie
openalex +1 more source
TriMag Microrobots: 3D‐Printed Microrobots for Magnetic Actuation, Imaging, and Hyperthermia
TriMag microrobots are two‐photon polymerized hydrogel structures embedded with in situ synthesized Fe3O4 and CoFe2O4 nanoparticles, enabling magnetic actuation, high‐resolution magnetic particle imaging (MPI), and efficient magnetothermal heating for deep‐tissue biomedical interventions including tracking, navigation, and tumor ablation.
Liuxi Xing +14 more
wiley +1 more source
Plant growth-promoting bacteria modulate metabolism and nitrogen accumulation to counteract drought damage in cactus pear plants. [PDF]
Dauala GA +17 more
europepmc +1 more source
INFLUENCE OF SODIUM SALICYLATE UPON THE ARTHRITIS OF RABBITS INOCULATED WITH NON-HEMOLYTIC STREPTOCOCCI [PDF]
Homer F. Swift, Ralph H. Boots
openalex +1 more source
Dendrimers Improve Apolipoprotein Nanoparticle mRNA Delivery to Immune Cells
Apolipoprotein nanoparticle (aNP) platform technology efficiently delivers RNA to immune cells following systemic administration. Here, it is demonstrated that incorporating polyvalent ionizable cationic dendrimers in aNPs enables robust mRNA complexation and functional delivery.
Mirre M. Trines +24 more
wiley +1 more source
Unleashing the synergistic interaction between Meloidogyne enterolobii and Fusarium sp. in guava wilt complex disease. [PDF]
Shravani +5 more
europepmc +1 more source
Virus Enhanced Microrobots for Biofilm Eradication
Biofilms resist antimicrobials across medicine, industry, and environments. We present virus‐conjugated microrobots synthesized hydrothermally and magnetically actuated. Their motion and viral specificity enable targeted binding, penetration, and delivery, outperforming bare microrobots.
Jyoti +3 more
wiley +1 more source
Early skin colonization by <i>Staphylococcus epidermidis</i> and <i>Staphylococcus aureus</i> reveals environment-dependent synergistic effects. [PDF]
Ngari C +4 more
europepmc +1 more source

