Results 31 to 40 of about 198,056 (257)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Briket Arang Tempurung Kawista (Limonia acidissima) Teraktivasi NaOH dengan Perekat Alami

Αl-Kimiya: Jurnal Ilmu Kimia dan Terapan, 2019
Penelitian tentang pemanfaatan tempurung tempurung kawista (Limonia acidissima) telah dilakukan sebagai bahan dasar pembuatan briket arang. Variabel jenis perekat alami berupa gel yang terbuat dari tepung beras, tepung ketan, dan tepung tapioka ...
Eny Yulianti, Raudatul Jannah, Lilik Miftahul Khoiroh, Vina Nurul Istighfarini   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Mobile technologies as a tools to support learning at the school course of inorganic chemistry

CTE Workshop Proceedings, 2017
In the article deals with the peculiarities and the use of electronic educational resources, including mobile technologies in the educational process in the study of chemistry.
T. I. Hranovska, M. V. Laptyeva
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

In the Footsteps of Alfred Werner: The Institute of Inorganic Chemistry at the University of Zurich

CHIMIA, 2008
Inorganic chemistry has a long-standing tradition at the University of Zurich starting with Carl Jacob Löwig, the first professor of chemistry.
Roger Alberto, Greta R. Patzke, Roland K. O. Sigel, Heinz G. Berke   +3 more
doaj   +1 more source

STRUCTURAL INORGANIC CHEMISTRY [PDF]

Nature, 1946
SINCE the first studies of crystal structures were made by the Braggs in 1913, there has been an ever-increasing flow of structure analyses carried out, first by the X-ray method alone, and later in addition by other techniques. For some time, while investigators-largely physicists-were exploring the possibilities of the new science and establishing ...
openaire   +1 more source

Multimodal Data‐Driven Microstructure Characterization

Advanced Engineering Materials, EarlyView.
A self‐consistent autonomous workflow for EBSP‐based microstructure segmentation by integrating PCA, GMM clustering, and cNMF with information‐theoretic parameter selection, requiring no user input. An optimal ROI size related to characteristic grain size is identified.
Qi Zhang, Santiago Benito, Özge Özgün, Sebastian Weber, Markus Stricker   +4 more
wiley   +1 more source

Biosugarcane-based carbon support for high-performance iron-based Fischer-Tropsch synthesis

iScience, 2021
Summary: Exploiting new carbon supports with adjustable metal-support interaction and low price is of prime importance to realize the maximum active iron efficiency and industrial-scale application of Fe-based catalysts for Fischer-Tropsch synthesis (FTS)
Jingyang Bai, Chuan Qin, Yanfei Xu, Yixiong Du, Guangyuan Ma, Mingyue Ding   +5 more
doaj   +1 more source

Tailoring Functional Properties of Ti–Ni–Cu Shape Memory Alloy Thin Films for MEMS Actuators

Advanced Engineering Materials, EarlyView.
A comprehensive study of critical parameters required to develop well‐performing Ti–Ni–Cu thin film shape memory alloy microactuators is provided. Materials science and device integration aspects are integrated by addressing structural and physical relationships using complementary characterization techniques as well as a practical fabrication solution
Elaheh Akbarnejad, Aleksander Kostka, Gowtham Arivanandhan, Yujiao Li, Alan Savan, Manfred Kohl, Alfred Ludwig   +6 more
wiley   +1 more source