Results 191 to 200 of about 211,797 (340)

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source

Insights into Bioactive Constituents from Pericarp of <i>Garcinia mangostana</i>: Anti-Inflammatory Effects via NF-κB/MAPK Modulation and M1/M2 Macrophage Polarization. [PDF]

Antioxidants (Basel)
Yang CS, Li SM, Chen JJ.
europepmc   +1 more source

(173) Ino [PDF]

, 2003
openaire   +1 more source

Inflammatory monocytes and NK cells play a crucial role in DNAM-1-dependent control of cytomegalovirus infection [PDF]

, 2016
Colonna, Marco, et al,
core   +2 more sources

Surfactant Dysfunction in SP-A ^−/− and iNOS ^−/− Mice with Mycoplasma Infection

, 2006
Judy M. Hickman‐Davis, Zhengdong Wang, German Alejandro Fierro-Perez, Patricia R. Chess, Grier P. Page, Sadis Matalon, Robert H. Notter   +6 more
openalex   +1 more source

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

Advanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, Fuxin Wei   +10 more
wiley   +1 more source

Elucidating the isorhamnetin-3-O-glucoside-iNOS interaction via molecular dynamics and Hirshfeld surface analyses. [PDF]

PLoS One
Khibech O, Bouammali H, Hammouti Y, Bouhrim M, Merzouki M, Abadi S, Al-Zharani M, Nasr FA, Qurtam AA, Bouammalli B, Challioui A.   +10 more
europepmc   +1 more source

Self‐Assembled Myricetin‐Arginine Conjugate Nanozymes for Targeted Suppression of Joint Inflammation and Osteoclastogenesis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Carrier‐free myricetin‐arginine conjugate nanozymes (MANZs) have been fabricated through a Mannich reaction and spontaneous self‐assembly. MANZs selectively accumulate in inflamed joints by targeting M1 macrophages via CAT2‐mediated uptake. The nanozymes can effectively modulate macrophage polarization, suppress osteoclast differentiation, and mitigate
Jiachang Hong, Penghao Ji, Jinxi An, Junchao Huang, Ziheng Bu, Xudong Zhang, Wei Liu, Tingyu Wu, Sen Wang, Wei Zhu, Yuhui Li, Jixian Wan, Sudan Xu, Minfeng Huo, Peng Wu   +14 more
wiley   +1 more source

Bioactive-Rich <i>Piper sarmentosum</i> Aqueous Extract Mitigates Osteoarthritic Pathology by Enhancing Anabolic Activity and Attenuating NO-Driven Catabolism in Human Chondrocytes. [PDF]

Biomedicines
Lee YT, Mohd Yunus MH, Abdul Rani R, Ng CY, Yazid MD, Ugusman A, Law JX.   +6 more
europepmc   +1 more source

INO volume 11 issue 3 Front matter [PDF]

, 1957
Rupert Emerson, Raymond Dennett, Norman Padelford, William Diebold, R Walter, Edgar Sharp, Furniss, W Kenneth, Leland Thompson, Robert Goodrich, H Triffin, Field Haviland, Joseph Richard Van Wagenen, Bryce Johnson, L Kirk, Quincy Wright, Mme Paul Bastid, John Goormaghtigh, Alfred Hero   +18 more
openalex   +1 more source