Results 221 to 230 of about 31,925 (249)
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Molecular and General Genetics MGG, 1988
Two complementary 24 base single stranded oligonucleotides containing randomly located inosine residues were synthesized in vitro. Once annealed, the two oligonucleotides were cloned into derivatives of ColE1 and transformed into Escherichia coli. Sequence analysis of 157 clones yielded 305 mutations. The pattern of the mutations revealed the following:
Patrice L. Nordmann +2 more
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Two complementary 24 base single stranded oligonucleotides containing randomly located inosine residues were synthesized in vitro. Once annealed, the two oligonucleotides were cloned into derivatives of ColE1 and transformed into Escherichia coli. Sequence analysis of 157 clones yielded 305 mutations. The pattern of the mutations revealed the following:
Patrice L. Nordmann +2 more
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Vasoactivity of inosine in the rat
Pharmacological Research Communications, 1980Summary Inosine increases the blood pressure in the rat independently of the autonomic nervous system. The mechanism of this hypertensive effect was investigated in 18 rats anesthetized with sodium pentobarbital. Inosine (0.01 M) infused at 0.03, 0.06, and 0.08 ml/min into the external jugular vein consistently caused a sustained, dose-dependent rise
Russell L. Prewitt, Jay M. Sullivan
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Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1971
Abstract Antibodies against a single minor base, inosine, have been prepared by immunizing rabbits with a conjugate of inosine and bovine serum albumin. The antisera obtained were fairly specific for inosine, only guanosine among the major nucleosides being capable of cross-reacting with them.
Uriel Z. Littauer +3 more
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Abstract Antibodies against a single minor base, inosine, have been prepared by immunizing rabbits with a conjugate of inosine and bovine serum albumin. The antisera obtained were fairly specific for inosine, only guanosine among the major nucleosides being capable of cross-reacting with them.
Uriel Z. Littauer +3 more
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On the tautomeric structure of inosine
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1971Abstract The suggestion that 6-keto and 6-enol tautomers of inosine may be of similar stability in neutral aqueous solution has been investigated by means of Raman spectroscopy. Spectra of aqueous solutions of inosine and its methylated analogs were obtained in the region 2000-200 cm−1 using argon laser excitation, and indicate that inosine exists ...
George J. Thomas, G.C. Medeiros
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Molecular Conformation of Inosine
Nature, 1969INOSINE is one of the rare nucleosides found in nucleic acids. It occurs especially in transfer ribonucleic acid where it appears to form part of a number of anticodons1,2. It can form a base pair with any one of the bases adenine, uracil or cytidine in the third codon1,2 position, and the possibility of atypical base pairs is part of the “wobble ...
P. Tollin, A. R. I. Munns
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Renal preservation with inosine
Urology, 1980Isosine improved post-transplantation function of canine kidneys subjected to thirty minutes of normothermic ischemia followed by flushing and twenty-four-hour cold storage. Inosine was not able to improve renal preservation when cold storage was extended to forty-eight hours after thirty minutes of normothermic ischemia.
August J. Maggio +3 more
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The Journal of Chemical Thermodynamics, 2005
Abstract The formation thermodynamic properties of crystalline and aqueous inosine have been determined by using a combination of calorimetric techniques. Oxygen bomb calorimetric measurements on crystalline inosine yielded a standard molar enthalpy of combustion of Δ c H m ∘ = - ( 4802.2 ± 4.5 ) kJ · mol - 1
Robert N. Goldberg +5 more
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Abstract The formation thermodynamic properties of crystalline and aqueous inosine have been determined by using a combination of calorimetric techniques. Oxygen bomb calorimetric measurements on crystalline inosine yielded a standard molar enthalpy of combustion of Δ c H m ∘ = - ( 4802.2 ± 4.5 ) kJ · mol - 1
Robert N. Goldberg +5 more
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Synthesis of Inosine Polyphosphates from Inosine 5’-Phosphate
Advanced Materials Research, 2014Treatment of inosine 5’-phosphate (IMP) with 2,2’-dithiodianiline/triphenylphosphine provided an efficient method for the synthesis of inosine 5′-phosphoropiperidate under mild conditions. Inosine 5’-triphosphate (ITP) and inosine 5′-diphosphate (IDP) were efficiently synthesized from inosine 5’-phosphoropiperidate via the activation P(V)—N bond by 4,5-
Jian Sun, Qi Sun, Shan Shan Gong
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Conversion of 5′-inosinic acid to inosine by Streptomyces aureus
Journal of Fermentation Technology, 1988Abstract The production of inosine by microbial conversion of 5′-inosinic acid (IMP) was investigated. Among the various strains of Streptomyces and Bacillus tested, Streptomyces aureus NCIB 9803 was selected for the microbial conversion process due to its high IMP-degrading activity.
Young Je Cho +4 more
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STABILITY OF INOSINIC ACID, INOSINE AND HYPOXANTHINE IN AQUEOUS SOLUTIONS
Journal of Food Science, 1972The stability of inosinic acid. inosine and hypoxanthine in aqueous solutions at 90°C was studied. Inosinic acid, inosine and hypoxanthine were separated by ion exchange chromatography and spectrometrically estimated. Reaction rates in the region pH 2–12 were calculated.
G. Janíček +2 more
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