Results 271 to 280 of about 86,294 (302)

VCTatDot and VCTatMLP: novel deep learning models with triadic attention embeddings for synergistic drug combination prediction. [PDF]

Sci Rep
Majidifar S, Hooshmand M.
europepmc   +1 more source

The Power of Old Hats: Rediscovering Inosine-EpPCR to Create Starting Libraries for Whole-Cell-SELEX. [PDF]

Biosensors (Basel)
Bolotnikov G, Kissmann AK, Gruber D, Bellmann A, Hasler R, Kleber C, Knoll W, Rosenau F.   +7 more
europepmc   +1 more source

Conformational Landscape of the Mycobacterial Inosine-5′-Monophosphate Dehydrogenase Octamerization Interface

Ondřej Bulvas, Zdeněk Knejzlı́k, Anatolij Filimoněnko, Tomáš Kouba, Iva Pichová   +4 more
openalex   +1 more source

Screening and evaluation of purines-degrading lactic acid bacteria isolated from traditional fermented foods in Yunnan Province and their uric acid-lowering effects <i>in vivo</i>. [PDF]

Front Microbiol
Liu Z, Zou XY, Yue J, Li S, Ou X, Huang C, Liu CJ, Li XR.   +7 more
europepmc   +1 more source

Effect and Mechanisms of Yiqi Jianpi Xiaoyu Prescription on Kidney Fibrosis on the Basis of Metabolomics and Experimental Validation. [PDF]

Food Sci Nutr
Lu K, Ye L, Jiang W, Cheng T, Xia H, Zhang P, Zhang B.   +6 more
europepmc   +1 more source

Multiomics analysis unveils an inosine-sensitive DNA damage response in neurogenic bladder after spinal cord injury. [PDF]

JCI Insight
Hashemi Gheinani A, Sack BS, Bigger-Allen A, Thaker H, Atta H, Lambrinos G, Costa K, Doyle C, Gharaee-Kermani M, Patalano S, Piper M, Cotellessa JF, Vitko D, Li H, Kadayil Prabhakaran M, Cristofaro V, Froehlich J, Lee RS, Yang W, Sullivan MP, Macoska JA, Adam RM.   +21 more
europepmc   +1 more source

Integrating tRNA gene epigenomics and expression with codon usage unravels an intricate connection with translatome dynamics in <i>Trypanosoma cruzi</i>. [PDF]

mBio
Silva HGS, Kimura S, Lima PLC, Pires DS, Waldor MK, da Cunha JPC.   +5 more
europepmc   +1 more source

Comparison of the total and individual purine content of commercial maintenance dog foods and therapeutic dog foods that may be prescribed to prevent urate urolithiasis. [PDF]

BMC Vet Res
Ishii CS, Scott KC, Abrahan C, Harmon TA, Colee JC, Queau Y, Biourge V, Garrett TJ, Hill RC.   +8 more
europepmc   +1 more source

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Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy

Science, 2020
Inosine modulates antitumor immunity Checkpoint blockade immunotherapy harnesses the immune system to kill cancer cells and has been used with great success to treat certain tumors, but not all cancer patients respond. The efficacy of checkpoint blockade
Lukas Franz Mager, Regula Burkhard, Nicola Pett   +2 more
exaly   +2 more sources

Protective Effects of Microbiome-Derived Inosine on Lipopolysaccharide-Induced Acute Liver Damage and Inflammation in Mice via Mediating the TLR4/NF-κB Pathway

Journal of Agricultural and Food Chemistry, 2021
This research assessed the anti-inflammatory and hepatoprotective properties of inosine and the associated mechanism. Inosine pretreatment significantly reduced the secretion of several inflammatory factors and serum alanine transaminase (ALT) and ...
Qunran Xiang, Bingyong Mao, Xin Tang
exaly   +2 more sources