Results 281 to 290 of about 86,294 (302)

Genome-wide quantification of ADAR adenosine-to-inosine RNA editing activity

Nature Methods, 2019
Shalom Hillel Roth, Erez Y Levanon, Eli Eisenberg   +2 more
exaly   +2 more sources

Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation

Nature Medicine, 2016
Konstantinos Stellos, Aikaterini Gatsiou, Kimon Stamatelopoulos   +2 more
exaly   +2 more sources

Inosine, Gut Microbiota, and Cancer Immunometabolism.

American Journal of Physiology. Endocrinology and Metabolism, 2022
This article briefly reviews cancer immunity and the role of gut microbiota in carcinogenesis, followed by an understanding of mechanisms by which inosine is involved in cancer immunometabolism.
Elham Samami, Elahe Aleebrahim-Dehkordi, Mehdi Mohebalizadeh, Shakila Yaribash, A. Saghazadeh, N. Rezaei   +5 more
semanticscholar   +1 more source

Inosine attenuates 3-nitropropionic acid-induced Huntington's disease-like symptoms in rats via the activation of the A2AR/BDNF/TrKB/ERK/CREB signaling pathway.

Life Science, 2022
Huntington's disease (HD) is an autosomal dominant inherited neurodegenerative disease characterized by involuntary bizarre movements, psychiatric symptoms, dementia, and early death.
Marwa El-Shamarka, Ayman E El-Sahar, M. A. Saad, N. Assaf, R. H. Sayed   +4 more
semanticscholar   +1 more source

Inosine‐Based Supramolecular Hydrogel for Highly Efficient PD‐L1 Blockade Therapy via Mediating CD8+ T Cells

Advanced Functional Materials, 2022
Inosine is proven to promote the proliferation and function of CD8+ cytotoxic lymphocytes (CD8+ T) under glucose restriction and enhance the efficacy of programmed cell death protein ligand‐1 (PD‐L1) blockade therapy.
J. Qi, T. Ding, Tiannan Liu, Xin Xia, Shihong Wu, Jiang Liu, Qianming Chen, Dunfang Zhang, Hang Zhao   +8 more
semanticscholar   +1 more source

Systematically Modulating Aptamer Affinity and Specificity by Guanosine-to-Inosine Substitution.

Analytical Chemistry, 2022
Aptamers are widely used in small molecule detection applications due to their specificity, stability, and cost effectiveness. One key challenge in utilizing aptamers in sensors is matching the binding affinity of the aptamer to the desired concentration
B. A. Manuel, Sierra A. Sterling, Aimee A Sanford, J. Heemstra   +3 more
semanticscholar   +1 more source

Investigating the Effect of Inosine on Brain Purinergic Receptors and Neurotrophic and Neuroinflammatory Parameters in an Experimental Model of Alzheimer’s Disease

Molecular Neurobiology, 2021
F. Teixeira, M. S. Soares, Eduardo B. Blödorn, W. Domingues, K. Reichert, Adriana M Zago, F. Carvalho, J. Gutierres, R. Gonçales, Marilda da Cruz Fernandes, V. Campos, Maria Rosa Chitolina, F. Stefanello, R. Spanevello   +13 more
semanticscholar   +1 more source

The protective effect of inosine against rotenone-induced Parkinson’s disease in mice; role of oxido-nitrosative stress, ERK phosphorylation, and A2AR expression

Naunyn-Schmiedeberg's Archives of Pharmacology, 2020
Marwa El-Shamarka, Magy R Kozman, B. Messiha   +2 more
semanticscholar   +1 more source

Redirection of Silencing Targets by Adenosine-to-Inosine Editing of miRNAs

Science, 2007
Yukio Kawahara, Boris Zinshteyn, Hisashi Iizasa   +2 more
exaly  

Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis

Nature Cell Biology, 2015
Cristina Ivan, Ka Ming Nip, Steven J M Jones   +2 more
exaly