Results 21 to 30 of about 14,200 (182)
Scientific Reports, 2022 Inosine 5′-monophosphate (5′-IMP) is an essential nucleotide for de novo nucleotide biosynthesis and metabolism of energy, proteins, and antioxidants. Nucleotides are conditionally essential, as they cannot be produced sufficiently rapidly to meet the ...
Lucas P. Bonagurio +4 more
doaj +1 more source
Determination of nucleotide and enzyme degradation in haddock (Melanogrammus aeglefinus) and herring (Clupea harengus) after high pressure processing [PDF]
PeerJ, 2019 Background The degradation of nucleotides and their enzymes had been widely used to evaluate fish freshness. Immediately after fish death, adenosine triphosphate (ATP) degrades into inosine-5-monophosphate (IMP) via adenosine-5-diphosphate (ADP) and ...
Nurul Ulfah Karim +5 more
doaj +2 more sources
Talanta Open, 2021 Hydrophilic interaction liquid chromatography using a zwitterionic phase, coupled with high-resolution mass spectrometry based on quadrupole and time-of-flight mass analyser (HILIC-Q-TOF-MS) is applied for the determination of four nucleobases (adenine ...
Marta Pastor-Belda +5 more
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Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate. [PDF]
PLoS ONE, 2015 Human NUDT16 is a member of the NUDIX hydrolase superfamily. After having been initially described as an mRNA decapping enzyme, recent studies conferred it a role as an "housecleaning" enzyme specialized in the removal of hazardous (deoxy)inosine ...
Lionel Trésaugues +7 more
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Profile of Nucleotides and Nucleosides in Taiwanese Human Milk
Pediatrics and Neonatology, 2011 Human milk–borne nucleotides and their related metabolic products have been reported to have important physiological roles in breast-fed infants. The purpose of this study was to measure the concentrations of free nucleotides and nucleosides in human ...
Kuo-Yu Liao +5 more
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Research Advances in Purine Phosphoribosyltransferases of Protozoan Parasites
Guangdong nongye kexue, 2023 Parasitic protozoa are single-celled organisms that have adapted to live in cells of humans and animals. The protozoan parasites include Leishmania spp., Trypanosoma spp., Plasmodium spp., Toxoplasma gondii, Cryptosporidium spp., and Eimeria spp., which ...
Zhihui YU +7 more
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The CBS subdomain of inosine 5′‐monophosphate dehydrogenase regulates purine nucleotide turnover [PDF]
Molecular Microbiology, 2008 SummaryInosine 5′‐monophosphate dehydrogenase (IMPDH) catalyses the rate‐limiting step in guanine nucleotide biosynthesis. IMPDH has an evolutionary conserved CBS subdomain of unknown function. The subdomain can be deleted without impairing the in vitro IMPDH catalytic activity and is the site for mutations associated with human retinitis pigmentosa. A
Maxim, Pimkin, George D, Markham
openaire +2 more sources
Potential Mechanisms Connecting Purine Metabolism and Cancer Therapy
Frontiers in Immunology, 2018 Unrestricted cell proliferation is a hallmark of cancer. Purines are basic components of nucleotides in cell proliferation, thus impaired purine metabolism is associated with the progression of cancer.
Jie Yin +9 more
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AppliedChem, 2023 Dietary nucleotides and nucleosides, primarily inosine monophosphate (IMP) and the adenine nucleotide pool (ANP), are widely considered as essential nutrients responsible for multiple biological functions.
Alar Sünter +10 more
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Enzymatic Extraction and Composition Analysis of 5′-Nucleotides from Shiitake Mushroom Stipe(香菇柄中5′-核苷酸的酶法提取及组成分析) [PDF]
Shipin kexue jishu xuebao, 2018 To improve the yield of 5′-nucleotides and increase the economic value of shiitake mushroom stipe, 5′-nucleotides were extracted from shiitake mushroom stipe by cellulase.
LI Shunfeng(李顺峰) +6 more
doaj +1 more source