Results 31 to 40 of about 14,200 (182)

A comparative study of meat quality and vibrational spectroscopic properties of different chicken breeds

Poultry Science, 2022
: Chicken breed is one of the key factors that influence meat quality. The quality attributes of breast meat from commercial broiler (CB), Thai native chicken (NC, Leung Hang Khao), and the crossbred Korat chicken (KC) were investigated via synchrotron ...
Sasikan Katemala, Amonrat Molee, Kanjana Thumanu, Jirawat Yongsawatdigul   +3 more
doaj   +1 more source

Neural stem cell–specific ITPA deficiency causes neural depolarization and epilepsy

JCI Insight, 2020
Inosine triphosphate pyrophosphatase (ITPA) hydrolyzes inosine triphosphate (ITP) and other deaminated purine nucleotides to the corresponding nucleoside monophosphates.
Yuichiro Koga, Daisuke Tsuchimoto, Yoshinori Hayashi, Nona Abolhassani, Yasuto Yoneshima, Kunihiko Sakumi, Hiroshi Nakanishi, Shinya Toyokuni, Yusaku Nakabeppu   +8 more
doaj   +1 more source

PAI: Predicting adenosine to inosine editing sites by using pseudo nucleotide compositions

Scientific Reports, 2016
AbstractThe adenosine to inosine (A-to-I) editing is the most prevalent kind of RNA editing and involves in many biological processes. Accurate identification of A-to-I editing site is invaluable for better understanding its biological functions. Due to the limitations of experimental methods, in the present study, a support vector machine based-model,
Wei Chen, Pengmian Feng, Hui Ding, Hao Lin   +3 more
openaire   +2 more sources

Different Characteristics and Nucleotide Binding Properties of Inosine Monophosphate Dehydrogenase (IMPDH) Isoforms

PLoS ONE, 2012
We recently reported that Inosine Monophosphate Dehydrogenase (IMPDH), a rate-limiting enzyme in de novo guanine nucleotide biosynthesis, clustered into macrostructures in response to decreased nucleotide levels and that there were differences between the IMPDH isoforms, IMPDH1 and IMPDH2.
Thomas, Elaine C., Gunter, Jennifer H., Webster, Julie A., Schieber, Nicole L., Oorschot, Viola, Parton, Robert G., Whitehead, Jonathan P.   +6 more
openaire   +5 more sources

ITPA (inosine triphosphate pyrophosphatase): From surveillance of nucleotide pools to human disease and pharmacogenetics [PDF]

Mutation Research/Reviews in Mutation Research, 2013
Cellular nucleotide pools are often contaminated by base analog nucleotides which interfere with a plethora of biological reactions, from DNA and RNA synthesis to cellular signaling. An evolutionarily conserved inosine triphosphate pyrophosphatase (ITPA) removes the non-canonical purine (d)NTPs inosine triphosphate and xanthosine triphosphate by ...
Peter D, Simone, Youri I, Pavlov, Gloria E O, Borgstahl   +2 more
openaire   +2 more sources

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Using 2D qNMR analysis to distinguish between frozen and frozen/thawed chicken meat and evaluate freshness

npj Science of Food, 2022
We identified key metabolites reflecting microbial spoilage and differentiated unfrozen meat from frozen/thawed (FT) using 2D qNMR analysis. Unfrozen and FT chicken breasts were prepared, individually aerobically packaged, and stored for 16 days at 2 °C.
Hyun Cheol Kim, Ki Ho Baek, Yee Eun Lee, Taemin Kang, Hyun Jun Kim, Dongheon Lee, Cheorun Jo   +6 more
doaj   +1 more source

Modulating Taste Perception in Newly Weaned Piglets: The Role of Palatability Additives in Enhancing Feed Intake and Performance

Animal Research and One Health, EarlyView.
Palatability enhancers modulate taste and smell, increasing feed acceptance, reducing weaning stress, and improving piglet performance. ABSTRACT The continuous growth of global agribusiness stimulates the search for alternatives that can enhance the performance and quality of life of production animals.
Luana Specht, Gabriela Altenhofen, Daiane Carvalho, Michele Fangmeier   +3 more
wiley   +1 more source

Evaluation of the taste profile of traditional Chinese Fuliji Red-cooked Chicken during processing

CyTA - Journal of Food, 2020
This study aimed to evaluate the taste profile of traditional Chinese Fuliji Red-cooked Chicken (FRCC) in five processing steps, consisting of raw, frying, stewing, vacuum-packaging and sterilization by measuring sodium chloride (NaCl), sugar, free amino
Guoyuan Xiong, Luyang Xia, Xueqin Gao, Xinxiang Zong, Jun Qi, Jingmin Jia   +5 more
doaj   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK pathways

Arthritis &Rheumatology, Accepted Article.
Introduction Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source