Results 81 to 90 of about 14,200 (182)

Guanine nucleotide biosynthesis blockade impairs MLL complex formation and sensitizes leukemias to menin inhibition

Nature Communications
Targeting the dependency of MLL-rearranged (MLLr) leukemias on menin with small molecule inhibitors has opened new therapeutic strategies for these poor-prognosis diseases.
Xiangguo Shi, Minhua Li, Zian Liu, Jonathan Tiessen, Yuan Li, Jing Zhou, Yudan Zhu, Swetha Mahesula, Qing Ding, Lin Tan, Mengdie Feng, Yuki Kageyama, Yusuke Hara, Jacob J. Tao, Xuan Luo, Kathryn A. Patras, Philip L. Lorenzi, Suming Huang, Alexandra M. Stevens, Koichi Takahashi, Ghayas C. Issa, Md. Abul Hassan Samee, Michalis Agathocleous, Daisuke Nakada   +23 more
doaj   +1 more source

Effect of microwave combined with steam pretreatment on the flavor and quality of Tibetan chicken soup

Food Chemistry: X
Conventional processing relies on time-consuming and intricate stewing methods, which hinder industrial-scale production of chicken soup. To address this limitation, this study investigated the effect of pretreatment cycle number on the quality of ...
Kai Dong, Xinyuan Huang, Yingmei Wu, Zhendong Liu, Yufang Guan, Hongbo Song, Fengping An, Xin Li, Erhao Zhang, Qun Huang   +9 more
doaj   +1 more source

Mixed infection of ITPase-encoding potyvirid and secovirid in Mercurialis perennis: evidences for a convergent euphorbia-specific viral counterstrike

Virology Journal
Background In cellular organisms, inosine triphosphate pyrophosphatases (ITPases) prevent the incorporation of mutagenic deaminated purines into nucleic acids.
Mathieu Mahillon, Justine Brodard, Nathalie Dubuis, Paul Gugerli, Arnaud G. Blouin, Olivier Schumpp   +5 more
doaj   +1 more source

Adenosine- and inosine-nucleotides in the phosphorus metabolism of muscle [PDF]

Biochemical Journal, 1942
openaire   +2 more sources

The Landscape and Regulatory Determinants of A-to-I RNA Editing in Escherichia coli and Pseudomonas aeruginosa Isolated From Patients With Urinary Tract and Ear Infections. [PDF]

J Infect Dis
Elias E, Keidar-Friedman D, Sorek N, Raz O, Tamir SO, Aspit L, Bar Yaacov D.   +6 more
europepmc   +1 more source

Purine Nucleotide Precursors in Preventing Myocardial Ischemia-Reperfusion Injury. [PDF]

Int J Mol Sci
Musial PT, Badtke PA, Zabielska-Kaczorowska MA.   +2 more
europepmc   +1 more source

A nanopore-based HIV-1 reference epitranscriptome. [PDF]

Nucleic Acids Res
Bosmeny MS, Pater AA, Zhang L, Larkai LL, Sha BE, Lyu Z, Damha MJ, Mamede JI, Gagnon KT.   +8 more
europepmc   +1 more source

Reliable Determination of ATP and Its Metabolites by LC-MS Using Blood Collection Tubes with and without Ectonucleotidase Inhibitors. [PDF]

ACS Pharmacol Transl Sci
Winzer R, Hiefner J, Hackbusch R, Link MA, Thomalla G, Tolosa E, Worthmann A.   +6 more
europepmc   +1 more source

Alpha-synuclein amyloids catalyze the degradation of ATP and other nucleotides. [PDF]

Sci Rep
Castillo-Cáceres C, Nova E, Diaz-Espinoza R.   +2 more
europepmc   +1 more source

Integrated analysis of transcriptome and metabolome reveals the molecular interactions and regulation of muscle flavor precursors in Tengchong Snow chickens and AA broilers. [PDF]

Front Vet Sci
Yang M, Zhang R, Zhao J, Jian Z, Wu H, Zi X, Wang K, Xu Z, Ge C, Jia J, Liu L, Dou T.   +11 more
europepmc   +1 more source