Results 181 to 190 of about 270,142 (371)

Overexpression of D-myo-inositol-3-phosphate synthase leads to elevated levels of inositol in Arabidopsis [PDF]

open access: yes, 2018
In this paper, we report on the generation of transgenic Arabidopsis plants containing elevated levels of the gene product encoding the enzyme catalysing the first committed step in inositol biosynthesis, D-myo-inositol-3-phosphate (Ins3P) synthase ...
Flores, Susan, Smart*, Cheryl
core  

Exosomes, autophagy, and cancer: A complex triad

open access: yesInternational Journal of Cancer, Volume 157, Issue 3, Page 405-415, 1 August 2025.
Abstract Cancer remains one of the leading causes of death worldwide. Despite remarkable progress in prevention, diagnosis, and therapy, the incidence of certain types of cancer persists, urging the identification of clinically relevant biomarkers and the development of novel therapeutic strategies to improve clinical outcomes and overcome treatment ...
María Guerra‐Andrés   +2 more
wiley   +1 more source

Towards the convergent therapeutic potential of G protein‐coupled receptors in autism spectrum disorders

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi   +6 more
wiley   +1 more source

Assessing quality, reliability and accuracy of polycystic ovary syndrome‐related content on TikTok: A video‐based cross‐sectional analysis

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Social networks share medical content with no peer‐review or fact‐checking. In the present study we aimed to assess the quality, reliability, and level of misinformation in TikTok videos about polycystic ovary syndrome (PCOS). Methods We performed a cross‐sectional analysis of TikTok videos retrieved using “PCOS” as the search term ...
Gaetano Riemma   +9 more
wiley   +1 more source

Gαq signalling from endosomes: A new conundrum

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract G‐protein‐coupled receptors (GPCRs) constitute the largest family of membrane receptors, and are involved in the transmission of a variety of extracellular stimuli such as hormones, neurotransmitters, light and odorants into intracellular responses.
Carole Daly, Bianca Plouffe
wiley   +1 more source

Investigation of endoplasmic reticulum stress parameters in patients with gestational diabetes mellitus: A prospective study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Our aim in this study was to evaluate the levels of Activating Transcription Factor‐6 (ATF‐6), Inositol‐Requiring Enzyme 1 (IRE‐1), and C/EBP‐Homologous Protein (CHOP), which are critical markers of endoplasmic reticulum (ER) stress, in patients with gestational diabetes mellitus (GDM), a condition increasingly recognized for its ...
Sevcan Sarıkaya   +6 more
wiley   +1 more source

Membrane Association of Lipoprotein Lipase and a cAMP-Binding Ectoprotein in Rat Adipocytes [PDF]

open access: yes, 1994
Bandlow, Wolfhard   +3 more
core   +1 more source

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