Results 261 to 270 of about 331,728 (400)

A Metabolite Score of Unintentional Weight Loss Explained a Substantial Proportion of Associated Mortality and Mobility Limitation Risk in a Biracial Older Cohort

open access: yesAging Cell, EarlyView.
A metabolite‐based score for short‐term unintentional weight loss was independently associated with mortality and mobility limitation risks in healthy older adults. It accounted for over 20% of the excess risk linked to unintentional weight loss, independent of lifestyle and medical history, suggesting a shared metabolic mechanism that remains ...
Shanshan Yao   +7 more
wiley   +1 more source

Myo-inositol may prevent gestational diabetes onset in overweight women: a randomized, controlled trial

open access: yesJournal of Maternal-Fetal & Neonatal Medicine, 2016
A. Santamaria   +7 more
semanticscholar   +1 more source

Relaxin‐2 improves type I diabetes mellitus‐induced erectile dysfunction in rats by protecting cavernous endothelial and smooth muscle function, and inhibiting penile fibrosis and apoptosis

open access: yesAndrology, EarlyView.
Abstract Background Diabetes mellitus‐induced erectile dysfunction (DMED) responds poorly to first‐line treatments, necessitating the development of new therapeutic strategies. Relaxin‐2 (RLX‐2) plays a crucial role in protecting vascular endothelium, vasodilatation, and antifibrosis in various diseases.
Bocheng Tu   +10 more
wiley   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

open access: yesBrain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li   +7 more
wiley   +1 more source

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