Results 261 to 270 of about 270,142 (371)

Age‐Dependent Regulation of Hippocampal Inflammation by the Mitochondrial Translocator Protein in Mice

open access: yesAging Cell, EarlyView.
The role of mitochondrial translocator protein (TSPO) in hippocampal inflammation is age‐dependent, with TSPO deletion drastically exacerbating inflammation in aged mice, while dampening it in young mice. This TSPO–aging interaction was linked to NF‐kβ and interferon regulatory transcriptional networks. TSPO deletion exacerbated age‐dependent depletion
Kei Onn Lai   +7 more
wiley   +1 more source

Biochemical Studies on Inositol

open access: hybrid, 1966
I‐Wen Chen, Frixos C. Charalampous
openalex   +1 more source

INOSITOL-REQUIRING MUTANTS OF SACCHAROMYCES CEREVISIAE [PDF]

open access: bronze, 1975
Michael R. Culbertson, Susan A. Henry
openalex   +1 more source

VDAC1‐Targeted NHK1 Peptide Recovers Mitochondrial Dysfunction Counteracting Amyloid‐β Oligomers Toxicity in Alzheimer's Disease

open access: yesAging Cell, EarlyView.
Amyloid‐β (Aβ) oligomers affect VDAC1 electrophysiology and the physiological metabolic cross‐talk between cytosol and mitochondria. The use of a small, synthetic VDAC1‐antagonist peptide, derived from hexokinase, restores mitochondrial functionality, and respiration in cellular models of Alzheimer's disease. ABSTRACT Mitochondrial dysfunction has been
Fabrizio Cavallaro   +10 more
wiley   +1 more source

Relaxin‐2 improves type I diabetes mellitus‐induced erectile dysfunction in rats by protecting cavernous endothelial and smooth muscle function, and inhibiting penile fibrosis and apoptosis

open access: yesAndrology, EarlyView.
Abstract Background Diabetes mellitus‐induced erectile dysfunction (DMED) responds poorly to first‐line treatments, necessitating the development of new therapeutic strategies. Relaxin‐2 (RLX‐2) plays a crucial role in protecting vascular endothelium, vasodilatation, and antifibrosis in various diseases.
Bocheng Tu   +10 more
wiley   +1 more source

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