Results 281 to 290 of about 270,142 (371)

Arrestin‐centred interactions at the membrane and their conformational determinants

British Journal of Pharmacology, EarlyView.
Abstract More than 30 years after their discovery, arrestins are recognised multiprotein scaffolds that play essential roles in G protein‐coupled receptor (GPCR) regulation and signalling. Originally named for their capacity to hinder GPCR coupling to G proteins and facilitate receptor desensitisation, arrestins have emerged as key hubs for a myriad of
Owen Underwood, Raphael Silvanus Haider, Julie Sanchez, Meritxell Canals   +3 more
wiley   +1 more source

Inositol Phosphates and Synthesizing Enzymes: Implications in Neurodegenerative Disorders. [PDF]

Biomolecules
Onu CJ, Adu M, Chakkour M, Kumar V, Greenberg ML.   +4 more
europepmc   +1 more source

The Biosynthesis of meso-Inositol by Cultured Mammalian Cells, and the Parabiotic Growth of Inositol-dependent and Inositol-independent Strains

, 1960
Harry Eagle, Bernard W. Agranoff, Esmond E. Snell   +2 more
openalex   +1 more source

G protein‐coupled receptor‐mediated autophagy in health and disease

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) constitute the largest and most diverse superfamily of mammalian transmembrane proteins. These receptors are involved in a wide range of physiological functions and are targets for more than a third of available drugs in the market. Autophagy is a cellular process involved in degrading damaged proteins and organelles
Devrim Öz‐Arslan, Zeynep Aslıhan Durer, Beki Kan   +2 more
wiley   +1 more source

Association of Myo-Inositol and Microlipodispersed Magnesium in Androgen-Dependent Dermatological Diseases: A Retrospective Study. [PDF]

Pharmaceuticals (Basel)
Pezza M, Carlomagno V, Sammarco E, Trischitta A, Ceddia C, Vitiello A, Baj G, Citi V, Colletti A.   +8 more
europepmc   +1 more source

Ligand bias and inverse agonism on 5‐HT2A receptor‐mediated modulation of G protein activity in post‐mortem human brain

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Whereas biased agonism on the 5‐HT2A receptor has been ascribed to hallucinogenic properties of psychedelics, no information about biased inverse agonism on this receptor is available. In schizophrenia, increased 5‐HT2A receptor constitutive activity has been suggested, highlighting the therapeutic relevance of inverse ...
Itziar Muneta‐Arrate, Patricia Miranda‐Azpiazu, Igor Horrillo, Rebeca Diez‐Alarcia, J. Javier Meana   +4 more
wiley   +1 more source

New insights into genome assembly at the chromosome-level of <i>Prunus tomentosa</i> in evolution and cold tolerance. [PDF]

Imeta
Jiu S, Manzoor MA, Lv Z, Chen B, Shen S, Xu Y, Liu M, Li C, Liu X, Fu Y, Zhang Q, Liu R, Zhang X, Wang S, Song X, Dong Y, Zhang C.   +16 more
europepmc   +1 more source

The Presence of Inositol in Genital Tract Secretions of the Female Rabbit

, 1962
A.T. Gregoire, D Gongsakdi, A.E. Rakoff
openalex   +1 more source

ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison, Clauda Abboud, Dayana Abboud, Abdulrasheed O. Abdulrahman, Ana‐Nicoleta Bondar, Julie Dam, Zafiroula Georgoussi, Jesús Giraldo, Anemari Horvat, Christos Karoussiotis, Alba Paz‐Castro, Miriam Scarpa, Hannes Schihada, Nicole Scholz, Bilge Güvenc Tuna, Nina Vardjan   +15 more
wiley   +1 more source

Towards Improved Bioavailability of Cereal Inositol Phosphates, <i>Myo</i>-Inositol and Phenolic Acids. [PDF]

Molecules
Żyła K, Duda A.
europepmc   +1 more source