Results 41 to 50 of about 345,398 (296)

Distribution and fatty acid composition of phosphoglycerides in normal human brain

Journal of Lipid Research, 1968
A thin-layer chromatographic procedure for the isolation of tissue phospholipids and their subsequent analysis is described. The method has been applied to the determination of the fatty acids of phosphoglycerides in human brain from the early fetal ...
Lars Svennerholm
doaj   +1 more source

When one size does not fit all: Reconsidering PCOS etiology, diagnosis, clinical subgroups, and subgroup-specific treatments

Endocrine and Metabolic Science
Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder that affects a large proportion of women. Due to its heterogeneity, the best diagnostic strategy has been a matter of contention.
V. Unfer, E. Kandaraki, L. Pkhaladze, S. Roseff, M.H. Vazquez-Levin, A.S. Laganà, C. Shiao-Yng, M.I.M. Yap-Garcia, N.D.E. Greene, C.O. Soulage, A. Bevilacqua, S. Benvenga, D. Barbaro, B. Pintaudi, A. Wdowiak, C. Aragona, Z. Kamenov, M. Appetecchia, G. Porcaro, I. Hernandez Marin, F. Facchinetti, T. Chiu, O. Pustotina, O. Papalou, M. Nordio, T. Cantelmi, P. Cavalli, I. Vucenik, R. D'Anna, V.R. Unfer, S. Dinicola, S. Salehpour, A. Stringaro, M. Montaninno Oliva, M. Tugushev, N. Prapas, M. Bizzarri, M.S.B. Espinola, C. Di Lorenzo, A.C. Ozay, J. Nestler   +40 more
doaj   +1 more source

An ATP-responsive metabolic cassette comprised of inositol tris/tetrakisphosphate kinase 1 (ITPK1) and inositol pentakisphosphate 2-kinase (IPK1) buffers diphosphosphoinositol phosphate levels

Biochemical Journal, 2020
Inositol polyphosphates are ubiquitous molecular signals in metazoans, as are their pyrophosphorylated derivatives that bear a so-called ‘high-energy’ phosphoanhydride bond.
H. Whitfield, G. White, Colleen Sprigg, A. M. Riley, B. Potter, A. Hemmings, C. Brearley   +6 more
semanticscholar   +1 more source

Inositol and herbal substances as elements of complementary therapy in patients with PCOS

Journal of Education, Health and Sport, 2023
Introduction: Polycystic ovary syndrome is a common hormonal disorder in women and the leading cause of female infertility. Traditional therapeutic methods often do not yield the expected results, hence the need to explore new treatment strategies ...
Arkadiusz Aab, Julia Zarańska, Kamila Kędra, Izabela Michalik, Maciej Bielak, Bartosz Zarański   +5 more
doaj   +1 more source

Inositol supplementation - known and possible applications

Journal of Education, Health and Sport, 2022
Introduction: Myo-inositol (MYO) and D-chiro-inositol are chemical compounds known to exert an impact on multiple signaling pathways of a human body. Due to its effects on insulin metabolism and ovaries’ hormone activity their use in polycystic ovary ...
Aleksandra Swora, Joanna Borowik, Wojciech Brodowski, Oliwer Sygacz, Piotr Pawłowski, Przemysław Żelazny, Joanna Filipczak, Sara Dankiewicz, Sebastian Bróż, Katarzyna Basta-Arciszewska   +9 more
doaj   +1 more source

Inositol Pyrophosphate Pyrotechnics [PDF]

Cell Metabolism, 2007
Physiologic roles of highly phosphorylated inositol phosphates, including those containing pyrophosphate groups, have been the focus of much recent interest. In the April 6, 2007 issue of Science, two papers (Lee et al., 2007; Mulugu et al., 2007) demonstrate the occurrence of a novel inositol pyrophosphate molecule in yeast and elucidate its role in ...
Bhandari, Rashna, Chakraborty, Anutosh, Snyder, Solomon H.   +2 more
openaire   +2 more sources

The inositol hexakisphosphate kinases IP6K1 and -2 regulate human cellular phosphate homeostasis, including XPR1-mediated phosphate export

Journal of Biological Chemistry, 2019
Phosphate's central role in most biochemical reactions in a living organism requires carefully maintained homeostasis. Although phosphate homeostasis in mammals has long been studied at the organismal level, the intracellular mechanisms controlling ...
Miranda S. C. Wilson, H. Jessen, A. Saiardi   +2 more
semanticscholar   +1 more source

Efficient Multi-Enzymes Immobilized on Porous Microspheres for Producing Inositol From Starch

Frontiers in Bioengineering and Biotechnology, 2020
In vitro synthetic enzymatic biosystem is considered to be the next generation of biomanufacturing platform. This biosystem contains multiple enzymes for the implementation of complicated biotransformatiom.
Pingping Han, Xigui Zhou, Chun You, Chun You   +3 more
doaj   +1 more source

A tale of two inositol trisphosphates. [PDF]

, 2016
Between spring 1982 and autumn 1984 the physiological role of Ins(1,4,5)P3 as a calcium-mobilizing second messenger was first suggested and then experimentally established.

core   +2 more sources

Calcium puffs are generic InsP₃-activated elementary calcium signals and are downregulated by prolonged hormonal stimulation to inhibit cellular calcium responses [PDF]

, 2001
Elementary Ca2+ signals, such as "Ca2+ puffs", which arise from the activation of inositol 1,4,5-trisphosphate receptors, are building blocks for local and global Ca2+ signalling.
Berridge, Michael J., Bootman, Martin D., De Smedt, Humbert, de Smet, Patrick, Holmes, Andrew, Lipp, Peter, Missiaen, Ludwig, Parys, Jan B., Thomas, David, Thuring, Jan, Tovey, Stephen C., Young, Kenneth W.   +11 more
core