Results 81 to 90 of about 3,938 (203)

Rice bran phytic acid (IP6) induces growth inhibition, cell cycle arrest and apoptosis on human colorectal adenocarcinoma cells [PDF]

open access: yes, 2010
Phytic acid (inositol hexaphosphate or IP6) is one of the bioactive compound that is present in cereals, nuts and legumes. IP6 is a naturally occurring polyphosphorylated carbohydrate, recognized to posses various significant health benefits including ...
Ismail, Norsharina   +5 more
core   +1 more source

Membrane‐dependent assembly of Bruton's tyrosine kinase mediated by the Proline‐rich region and SH3 domain

open access: yesProtein Science, Volume 34, Issue 8, August 2025.
Abstract Cellular membranes provide a unique platform for interactions that drive emergent behaviors in protein dynamics and cellular signaling, distinct from those observed in solution. We investigated the proline‐rich region (PRR) and Src Homology 3 (SH3) domains of Bruton's tyrosine kinase (Btk) and its phase separation driven by the weak ...
Alexander D. Fenton, Jean K. Chung
wiley   +1 more source

Complete Immunophenotypic Reversal of Chronic Lymphocytic Leukaemia With High Dose Parenteral Methylcobalamin: A Case Report and Brief Review of Cobalamin in Cancer

open access: yesCancer Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background Supposed ‘spontaneous’ remissions in chronic lymphocytic leukaemia (CLL) are extremely rare. By the most stringent immunophenotypic criteria, there are only seven cases to date of unexplained, immune system effected cures. A historic review of this phenomenon is presented as context for this eighth case of CLL immunophenotypic ...
Carmen Wheatley
wiley   +1 more source

Effects of Phytic Acid Extracted From Rice Bran on Azoxymethane-Induced Colon Carcinogenesis in Rats [PDF]

open access: yes, 2008
This research is carried out to study the potential of phytic acid extracted from rice bran in the suppression of colon carcinogenesis in rats. In the optimization of phytic acid extraction, results showed 5% H2S04 in pH 0.6 and 30 minutes of extraction
Saad, Norazalina
core  

Metabolic insights of lactic acid bacteria in reducing off‐flavors and antinutrients in plant‐based fermented dairy alternatives

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 2, March 2025.
Abstract Multiple sensorial, technological, and nutritional challenges must be overcome when developing plant‐based fermented dairy alternatives (PBFDA) to mimic their dairy counterparts. The elimination of plant‐derived off‐flavors (green, earthy, bitter, astringent) and the degradation of antinutrients are crucial quality factors highlighted by the ...
Guillermo Eduardo Sedó Molina   +5 more
wiley   +1 more source

Study of superoxide dismutase's expression in the colon produced by azoxymethane and inositol hexaphosfate's paper, in mice Estudo da expressão de superóxido dismutase no cólon produzida por azoximetano e o papel do inositol hexafosfato, em ratos

open access: yesActa Cirúrgica Brasileira, 2006
PURPOSE: To investigate the expression of superoxide dismutase (SOD), with use of antioxidant inositol hexaphosfate, in the presence of the carcinogen azoxymethane, in FCA of colon rats.
Eva Glória Abrão Siufi do Amaral   +3 more
doaj   +1 more source

Dietary Phytase: an ideal approach for a cost effective and low-polluting aquafeed [PDF]

open access: yes, 2004
Global fishmeal production from wild-catch sources cannot continue to increase indefinitely; suitable alternatives have to be found for sustainable aquaculture.
Baruah, K.   +3 more
core  

Determination of phytic acid in urine by inductively coupled plasma mass spectrometry [PDF]

open access: yes, 2005
The aim of this work is to provide a simple and accurate analytical procedure to easily determine phytic acid in urine, in contrast with time-consuming current ...
Muñoz Martínez, José Antonio   +1 more
core   +1 more source

Precise Engineering and Efficient Biosynthesis of Robust and High‐Activity Human Haemoglobin for Artificial Oxygen Carriers

open access: yesMicrobial Biotechnology, Volume 18, Issue 3, March 2025.
The stable human haemoglobin variant was obtained through the design of novel high‐throughput screening strategies and methods. Furthermore, the supply level of heme in the production host was enhanced. Ultimately, an robust human haemoglobin was achieved with stronger stability, lower heme loss rate, lower autoxidation rate, more efficient oxygen ...
Fan Liu   +5 more
wiley   +1 more source

The Combined Repetitive Oligopeptides of Clostridium difficile Toxin A Counteract Premature Cleavage of the Glucosyl-Transferase Domain by Stabilizing Protein Conformation

open access: yesToxins, 2014
Toxin A (TcdA) and B (TcdB) from Clostridium difficile enter host cells by receptor-mediated endocytosis. A prerequisite for proper toxin action is the intracellular release of the glucosyltransferase domain by an inherent cysteine protease, which is ...
Alexandra Olling   +7 more
doaj   +1 more source

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