Results 231 to 240 of about 30,835 (333)

Temporal Stretch‐Induced Nuclear Mechanosensing Coordinates Early Chromatin Accessibility and Genome Protection

Advanced Science, Volume 13, Issue 5, 27 January 2026.
Cyclic stretching of fibroblasts triggers coordinated nuclear mechanosensing events, including calcium ion release, perinuclear actin assembly, emerin translocation, and H3K9me3 loss, increasing chromatin accessibility for specific genes related to mechanotransduction and repair.
Hye‐Won Shim, Ji‐Young Yoon, Hwalim Lee, Shanika Karunasagara, Cheng Ji Li, Yongdae Shin, Sukbum Hong, Dong‐Joon Lee, Jung‐Hwan Lee, Kam W. Leong, Hae‐Won Kim   +10 more
wiley   +1 more source

Inositol phosphates and phosphoinositides activate insulin-degrading enzyme, while phosphoinositides also mediate binding to endosomes. [PDF]

Proc Natl Acad Sci U S A, 2017
Song ES, Jang H, Guo HF, Juliano MA, Juliano L, Morris AJ, Galperin E, Rodgers DW, Hersh LB.   +8 more
europepmc   +1 more source

Crosstalk between Ras and inositol phosphate signaling revealed by lithium action on inositol monophosphatase in Schizophyllum commune

, 2019
Reyna Murry, Olaf Kniemeyer, Katrin Krause, Adolfo Saiardi, Erika Kothe   +4 more
openalex   +1 more source

Molecular Insights into Fungal Glycosylphosphatidylinositol Transamidase Complex

Advanced Science, Volume 13, Issue 2, 9 January 2026.
The glycosylphosphatidylinositol (GPI) biosynthesis pathway is critical for antifungal drug development. This study reports three cryo‐electron microscopy structures of fungal GPI transamidase (GPIT), captured in two substrate‐bound states and a novel dimeric assembly.
Zhengkang Hua, Xuyang Ding, Yanan Wu, Di Zhang, Xinlin Hu, Ping Yang, Jiameng Li, Yi Tan, Junbo Liu, Mingjie Zhang, Min Zhang, Xiaotian Liu, Hongjun Yu   +12 more
wiley   +1 more source

Effect of lidocaine on inositol phosphate metabolism of chochlea sensory epithelium.A consideration on susurrus aurium control mechanisms by lidocaine.

, 1994
IKU OGAWA
openalex   +2 more sources

Stimulus-response coupling in monocytes infected with Leishmania. Attenuation of calcium transients is related to defective agonist-induced accumulation of inositol phosphates. [PDF]

, 1992
Martin Olivier, K.G. Baimbridge, Neil E. Reiner   +2 more
openalex   +1 more source

PACS‐2 Mitigates NPSC Apoptosis and Intervertebral Disc Degeneration by Preserving MAM Integrity via the SP1/LRRK2/Mfn2 Axis

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This study investigates the role of PACS‐2 in IDD, demonstrating that it suppresses the nuclear translocation of SP1, thereby downregulating its downstream target LRRK2. This reduces LRRK2‐mediated ubiquitination and degradation of Mfn2 through the JNK pathway, preserving MAM integrity and promoting NPSC survival.
Liang Kang, Jiaqi Wang, Chenhao Zhao, Qiuwei Li, Zhigang Zhang, Huaqing Zhang, Chongyu Jia, Luping Zhou, Yanxin Wang, Yu Chen, Kaixuan Li, Xu Yan, Jie Fang, Haibao Wang, Dandan Wang, Pingping Su, Jingyu Zhang, Zhiwei Chen, Renjie Zhang, Cailiang Shen   +19 more
wiley   +1 more source

Fibrinogen - a possible extracellular target for inositol phosphates. [PDF]

Messenger (Los Angel), 2012
Grint T, Riley AM, Mills SJ, Potter BV, Safrany ST.   +4 more
europepmc   +1 more source

Release and Transformation of Inorganic Elements in Combustion of a High-Phosphorus Fuel [PDF]

, 2011
Castro, Maria, Dam-Johansen, Kim, Frandsen, Flemming, Glarborg, Peter, Jensen, Peter Arendt, Lundtorp, Kasper, Røkke, Martin, Wu, Hao   +7 more
core   +1 more source

Triple‐Negative Breast Cancer Cells Resist Natural Killer Cell‐Mediated Killing Through Interleukin‐11 Trans‐Signaling

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Triple‐negative breast cancer cells express high levels of interleukin‐11 (IL‐11) that can form complexes with soluble IL‐11 receptor (sIL‐11R). These complexes can bind to gp130 on the membrane of natural killer (NK) cells through trans‐signaling to activate JAK1/STAT1/3/p21 downstream pathway.
Hongmei Yang, Hao Jia, Renfei Wu, Haibo Tong, Liping Chen, Kathy Qian Luo   +5 more
wiley   +1 more source