Results 291 to 300 of about 30,835 (333)
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Paosphorothioate Analogues of Inositol Phosphates
Phosphorus, Sulfur, and Silicon and the Related Elements, 1990Abstract Novel analogues of the intracellular second messenger D-myo-inositol 1,4,5-trisphosphate, which possess phosphorothioate groups in place of phosphate groups have been synthesized. They exhibit unusual biological properties which will be of considerable application in understanding the phosphoinositide cycle.
Allan Cooke +3 more
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Inositol Phosphate Metabolism and Signal Transduction
American Review of Respiratory Disease, 1990Activation of a variety of cell surface receptors results in a biphasic increase in the cytoplasmic Ca2+ concentration, due to the release or mobilization of intracellular Ca2+ stores and to the entry of Ca2+ from the extracellular space. Stimulation of these same receptors also results in the hydrolysis of the minor plasma membrane phospholipid ...
A R, Hughes +3 more
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Gradient ion chromatography of inositol phosphates
Analytical Biochemistry, 1988Inositol phosphates including phytic acid were separated in 30 min by gradient ion chromatography with postcolumn derivatization. All four pentakisphosphates were resolved, while four tetrakisphosphate peaks were detected. The limits of detection for all polyphosphates, including tris- and bisphosphates, were between 1 and 2 nmol.
B Q, Phillippy, J M, Bland
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Inositol Phosphate Metabolism During Myocardial Ischemia
Journal of Molecular and Cellular Cardiology, 1997Inositol phosphate release in intact heart in response to norepinephrine involves primarily release of inositol(1,4)bisphosphate (Ins(1,4)P2) rather than inositol(1,4,5)trisphosphate (Ins(1,4,5)P3) but Ins(1,4,5)P3 release predominates under conditions of post-ischemic reperfusion.
E A, Woodcock +3 more
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Inositol Phosphate Second Messengers
1990Abstract The role of inositol lipid hydrolysis in receptor-mediated cell signalling was first suggested by Michell in the mid-1970s (1). However, the current growth in interest in this subject probably stems from the more recent realization that receptor-mediated hydrolysis of phosphatidylinositol 4,5-bisphosphate [Ptdlns(4,5)P2 ...
C J Kirk, A J Morris,, S B Shears
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Inositol Phosphates: Pinitol 4-Phosphate and (-)-Inositol 3-Phosphate
Journal of the American Chemical Society, 1958Gordon L. Kilgour, Clinton E. Ballou
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Inositol lipids and phosphates
Current Opinion in Cell Biology, 1990C P, Downes, A N, Carter
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