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Brain SciencesTraumatic brain injury (TBI) and subarachnoid hemorrhage (SAH) are critical neurological conditions that necessitate specialized care in the Intensive Care Unit (ICU).
Michele Salvagno +2 more
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Role of Arterial Serum Lactate as a Predictor of Undifferentiated Shock on Admission and its Outcome- A Cohort Study [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Patients with elevated serum lactate levels may be at risk for considerable morbidity and mortality and require a prompt, thoughtful and systematic approach for diagnosis and treatment.
Avadhesh Kumar Sharma +4 more
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Cardiogenic shock - novelty and emerging therapeutic concepts [PDF]
Българска кардиология, 2022 The cardiogenic shock is a state of low cardiac output, primarily due to cardiac dysfunction, which leads to severe organ hypoperfusion with tissue hypoxia and increased lactate levels. It presents a severe complication with a prevalence of around 15% of
I. Petrov, Z. Stankov, S. Vasilev
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Frontiers in Cardiovascular Medicine, 2022 Left ventricular assist device (LVAD) therapy has been instrumental in saving lives of patients with end-stage heart failure (HF). Recent generation devices have short-to-mid-term survival rates close to heart transplantation. Unfortunately, up to 1 in 4
Mahmoud Abdelshafy +15 more
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Frontiers in Cardiovascular Medicine, 2023 The role of the beta-adrenergic signaling pathway in heart failure (HF) is pivotal. Early blockade of this pathway with beta-blocker (BB) therapy is recommended as the first-line medication for patients with HF and reduced ejection fraction (HFrEF ...
Guillaume Schurtz +19 more
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Advanced heart failure: state of the art and future directions [PDF]
Reviews in Cardiovascular Medicine, 2022 Advanced heart failure is a clinical challenge that requires a pathophysiological-based approach. As the field has been the subject of multiple reviews, the objective of this paper is not to duplicate these publications but rather to offer practical ...
Daniele Masarone +3 more
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McGill Journal of Medicine, 2022 Shock is a life-threatening pathophysiologic state referring to inadequate organ perfusion, which can progress to end-organ dysfunction and eventually, multiple organ failure and death. The diagnosis of shock is clinical, necessitating good understanding
Janet Chan
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The cardiac work-loop technique:An in vitro model for identifying and profiling drug-induced changes in inotropy using rat papillary muscles [PDF]
, 2020 The cardiac work-loop technique closely mimics the intrinsic in vivo movement and characteristics of cardiac muscle function. In this study, six known inotropes were profiled using the work-loop technique to evaluate the potential of this method to ...
AJ Taberner +56 more
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Dobutamine-Induced Myoclonus in a Peritoneal Dialysis Patient: Case Report
Kidney Medicine, 2023 Dobutamine is a weak beta-1 and a potent beta-2 adrenergic agonist commonly used to treat patients in cardiogenic shock. It enhances myocardial contractibility, increasing cardiac output.
Edva Noel +5 more
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Diuretic resistance in patients with chronic heart failure: mechanisms, prevention, and treatment
Бюллетень сибирской медицины, 2022 The authors analyzed the problem of diuretic resistance (DR) in patients with chronic heart failure (CHF). Most of the symptoms and signs of CHF are associated with hypervolemia and vascular congestion in the systemic and pulmonary circulation.
V. V. Kalyuzhin +11 more
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