Results 201 to 210 of about 29,730 (250)
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Positive inotropic stimulation
Current Opinion in Critical Care, 2002Adrenergic receptors transduce signals through the G proteins to regulate cardiac function. The catecholamines, via alpha- and beta-adrenergic receptor (beta-AR) stimulation, may play a role in the development of heart failure. Norepinephrine and isoproterenol can induce cardiac myocyte apoptosis.
Marc, Leone +2 more
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Annual Review of Pharmacology and Toxicology, 1984
A large number of naturally occurring and synthetically prepared chemical agents produce a positive inotropic effect on the heart. Analogues of these compounds have been isolated, prepared, and tested, and a number of them also have positive inotropic effects (see Tables 1-6).
A E, Farah, A A, Alousi, R P, Schwarz
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A large number of naturally occurring and synthetically prepared chemical agents produce a positive inotropic effect on the heart. Analogues of these compounds have been isolated, prepared, and tested, and a number of them also have positive inotropic effects (see Tables 1-6).
A E, Farah, A A, Alousi, R P, Schwarz
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Inotropic Activities of Imidazopyridines
Archiv der Pharmazie, 1990AbstractA series of 2‐substituted 1H‐imidazo[4,5‐b]pyridines and the isomeric 1H‐imidazo[4,5‐c]pyridine derivatives has been prepared and evaluated as inotropic agents. The 1H‐imidazo‐[4,5‐b] derivatives were found to be consistently more potent than their isomers in the [4,5‐c] series in isolated guinea pig papillary muscle preparations.
Paul Barraclough +12 more
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Inotropic actions of eicosanoids
Basic Research in Cardiology, 1992Eicosanoids (prostaglandins, leukotrienes, thromboxane A2 and other metabolites of C-20 polyunsaturated fatty acids) have numerous effects in the cardiovascular system. Direct inotropic actions have been repeatedly described, but appear in only very few cases to be due to direct modification of the inotropic state of the heart.
K, Schrör, T, Hohlfeld
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Pediatric Emergency Care, 2018
Abstract Sepsis, severe sepsis, and septic shock represent a dynamic clinical syndrome involving a systemic inflammatory response, circulatory changes, and end-organ dysfunction from an infection. Early aggressive management to restore perfusion and/or improve hypotension is critical to improving outcomes.
Drew Taylor, Louden, Lori Ellen, Rutman
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Abstract Sepsis, severe sepsis, and septic shock represent a dynamic clinical syndrome involving a systemic inflammatory response, circulatory changes, and end-organ dysfunction from an infection. Early aggressive management to restore perfusion and/or improve hypotension is critical to improving outcomes.
Drew Taylor, Louden, Lori Ellen, Rutman
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Pharmacotherapeutics of Positive Inotropes
AORN Journal, 2000ABSTRACTPharmacology is integrated in all areas of nursing practice. From the most basic entry level to the most advanced clinical practice, nursing curriculums are not complete without pharmacology. The word “pharmacology” often makes nurses and other health care professionals feel uneasy.
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Amrinone: Is it the inotrope of choice?
Journal of Cardiothoracic Anesthesia, 1989In the treatment of acute heart failure, conventional therapy with epinephrine, norepinephrine, dopamine, and dobutamine may be used effectively to treat inotropic abnormalities. However, the addition of a vasodilator to catecholamine therapy may be needed to help improve lusitropic function.
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Anaesthesia & Intensive Care Medicine, 2021
Shailendra K. Motwani, Helen Saunders
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Shailendra K. Motwani, Helen Saunders
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Sympathomimetics, Inotropics, and Vasodilators
AACN Advanced Critical Care, 1992Management of the critically ill patient often necessitates the use of multiple inotropic and vasoactive medications. This article offers a concise, clinical reference to guide the practicing clinician in the use of these agents. The focus is on parenteral agents used for acute rather than chronic management. Physiologic concepts basic to understanding
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