Results 91 to 100 of about 473,924 (251)

Cazarin and Derollo et al Figure 8 and Supplemental Figures 8 and 9: MetaboAnalyst Metabolite Set Enrichment Analysis (MSEA) Input Files, R code, and output filesSource data for MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis

open access: gold, 2023
Brian J. Altman   +13 more
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

National Key Economic Area Multiplier Impact On Malaysian Economy: An Input-Output Analysis

open access: yesInternational Journal of Management Studies, 2011
The ultimate aim of this research is to provide an analysis of the impact multipliers on the Malaysian economy for 12 NKEA sectors. Economic activity is a complicated web of interdependent behaviour.
Siti Nadiah Ahmad Fuad   +1 more
doaj  

Propagation effects of taxes in Romania: An input-output analysis [PDF]

open access: yesRevista Romana de Economie, 2010
The Input-Output model (IO) is an important tool of economic analysis, providing a predictive analysis framework for economic changes, if properly used. In developing measures, strategies, etc.
GHEORGHE ZAMAN   +2 more
doaj  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

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