Results 121 to 130 of about 564,662 (259)

Genoarchitecture and input-output organization of the mouse basal ganglia and thalamic parafascicular nucleus. [PDF]

Nat Neurosci
Wang Q, Bhandiwad A, Gouwens NW, Yao S, Wang Y, Kuang X, Li A, Li X, Dalley R, Kuo HC, Lesnar P, Xu W, Mallory M, Li Y, El-Hifnawi L, Ahmadinia L, Ouellette B, Kruse L, Ng L, Gong H, Luo Q, Kunst M, van Velthoven CTJ, Yao Z, Sorensen SA, Zeng H.   +25 more
europepmc   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Decoupling between activation time and steady-state level in input-output responses. [PDF]

PLoS Comput Biol
Ravanelli G, Nam KM, Gunawardena J, Martinez-Corral R.   +3 more
europepmc   +1 more source

Input-output Characteristics

Japanese Journal of Radiological Technology, 2009
openaire   +2 more sources

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Linking Global Integrated Assessment and Hybrid Input-Output Models To Support Steel Decarbonization Policies in Europe. [PDF]

Environ Sci Technol
Ghezzi D, Rinaldi L, Horowitz R, van de Ven DJ, Holtz G, Jülich A, Rocco MV.   +6 more
europepmc   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

Computing the effects of excitatory-inhibitory balance on neuronal input-output properties. [PDF]

PLoS Comput Biol
Reyes AD.
europepmc   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

BEDRIJFSECONOMISCHE BETEKENIS VAN DE INPUT-OUTPUT ANALYSE [PDF]

MAB, 1974
C. Van Halem
doaj   +3 more sources