Results 51 to 60 of about 562,948 (256)

Lithuanian production modeling

open access: yesLietuvos Matematikos Rinkinys, 2005
Possibilities of production and its components in Lithuania modeling were analyzed in this paper. It is important to do good forecasts for production. Indicators which have strong influence on production were found. The obtained models explain structure
Nomeda Bratčikovienė
doaj   +3 more sources

Evaluasi program pelaksanaan kelas ibu balita di wilayah kerja dinas kesehatan kabupaten banjarnegara

open access: yesJunal Kebidanan Dan Keperawatan Aisyiyah, 2018
Penelitian ini bertujuan untuk mengetahui evaluasi pelaksanaan kelas ibu balita di wilayah kerja Dinas Kesehatan Kabupaten Banjarnegara. Metode penelitian deskriptif dengan pendekatan cross sectional. Rancangan penelitian observasi dan wawancara.
Lia Aria Ratmawati
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Research into the methods of analysing the productivity indicators of transport terminals [PDF]

open access: yesTransport, 2009
The measurement of terminal productivity is the issue of extreme importance to both terminal owners and management and customers. As the sector of transport is highly intensive in terms of investments into the infrastructure, the productivity of a ...
Ilona Jaržemskienė
doaj   +1 more source

THE MAGIC TRIANGLE OF INPUT-OUTPUT TABLES

open access: yesWorld Review of Political Economy, 2010
Input-output tables (I-O tables) can play an important role in delivering a suitable data base for studies on sustainable development.
Carsten Stahmer
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Evaluation of Home Care Service Program in Batua Public Health Center of Majority in Working Area of Makassar City

open access: yesWindow of Health, 2018
Home Care program started in the Stone Clinic from may 2014 by the Government of the city of Makassar. He had to do in a program evaluation is a process whereby an orderly and systematic there is scope in the evaluation i.e.
Nurwahidah Kasim   +2 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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