Results 121 to 130 of about 3,024,533 (298)

Input random processes of chemical-engineering objects simulation

Тонкие химические технологии, 2006
It is revealed, that consideration of chemical-engineering objects’ random components of input and output characteristics enables to determine more subtle characteristics of their operation.
V. I. Bozhko
doaj  

STATIONARY STOCHASTIC INPUT FLOW MODELING OF BRANCHED CONVEYOR SYSTEMS

Сучасні інформаційні системи
The object of research is stochastic stationary input material flow of a conveyor-type transport system. Subject of research is a method for generating realizations of a stationary stochastic input flow of material on the basis of experimental data. The
Oleh Pihnastyi , Victoriya Usik , Anna Burduk   +2 more
doaj   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Methodological aspects of the study of quasiisoentropic air compression in a flat supersonic inlet device of a power plant with GTE

Авіаційно-космічна техніка та технологія
The subject of the research is the parameters and characteristics of the supersonic part of the supersonic input device of external compression, namely: the coefficient of preservation of the full pressure of the supersonic part of the flat supersonic ...
Artem Khorokhordin, Mykhailo Mitrakhovych   +1 more
doaj   +1 more source

Application of Advanced Numerical Methods in the Identification of Selected Parameters of Synchronous Machines [PDF]

Journal of Electrical and Electronics Engineering, 2013
In this paper are analyzed the impacts of change of basic electrical parameters on input/output characteristics of synchronous machine. Some of these impacts can be considered as single-valued functionsand they can be used for identification of missing ...
UHRIK Milan
doaj  

Research on fluidics, valves, and proportional amplifiers [PDF]

Research and development being conducted at the Systems and Controls Laboratory is reviewed. Static characteristics (supply, input, transfer, output, and noise characteristics) of laminar proportional amplifiers were investigated.

core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Variable-Fidelity Simulation Models and Sparse Gradient Updates for Cost-Efficient Optimization of Compact Antenna Input Characteristics. [PDF]

Sensors (Basel), 2019
Koziel S, Pietrenko-Dabrowska A.
europepmc   +1 more source