Results 51 to 60 of about 3,243,208 (249)
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Proposed input for determining longitudinal aerodynamic parameters for the space shuttle [PDF]
A control input form to improve the identification of longitudinal aerodynamic parameters for the Space Shuttle, especially at low Mach numbers, has been proposed.
Suit, W. T.
core +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Parameter setting and input reduction
, 2008 The language acquisition procedure identifies certain properties of the target grammar before others. The evidence from the input is processed in a stepwise order. Section 1 equates that order and its typical effects with an order of parameter setting.
Arnold Ernest Evers +1 more
openaire +3 more sources
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Operators for transforming kernels into quasi-local kernels that improve SVM accuracy [PDF]
, 2008 Motivated by the crucial role that locality plays in various learning approaches, we present, in the framework of kernel machines for classification, a novel family of operators on kernels able to integrate local information into any kernel obtaining ...
Blanzieri, Enrico, Segata, Nicola
core +1 more source
, 2018 Inverse Uncertainty Quantification (UQ) is a process to quantify the uncertainties in random input parameters while achieving consistency between code simulations and physical observations. In this paper, we performed inverse UQ using an improved modular
Kozlowski, Tomasz +3 more
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
How stable are transport model results to changes of resonance parameters? A UrQMD model study
, 2012 The Ultrarelativistic Quantum Molecular Dynamics [UrQMD] model is widely used to simulate heavy ion collisions in broad energy ranges. It consists of various components to implement the different physical processes underlying the transport approach.
Bleicher, Marcus +3 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source