Results 41 to 50 of about 9,347 (266)
As a form of literacy, graffiti has existed throughout the ages. Many researches on epigraphy show that many examples of graffiti were left intact from the period of the Polish-Lithuanian Commonwealth.
Kšištof Tolkačevski
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
We prove that for every smooth Jordan curve $γ\subset \mathbb{C}$ and for every set $Q \subset \mathbb{C}$ of six concyclic points, there exists a non-constant quadratic polynomial $p \in \mathbb{C}[z]$ such that $p(Q) \subset γ$. The proof relies on a theorem of Fukaya and Irie.
Greene, Joshua Evan, Lobb, Andrew
openaire +2 more sources
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
“Serbian land” in the Tărnovо inscription of John Asen II in the light of the political and geographical terminology of the time [PDF]
This study examines the notion of friendship depicted in the epistolary corpus of Euthymios Malakes who served as bishop of Neai Patrai during the second half of the twelfth century.
Komatina Ivana, Komatina Predrag
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Through a simple wall, a transparent element of everyday life, Stanisław Grochowiak’s poems enable one to uncover the existential concrete element, matter endowed with an amazing hypnagogic potential, a chronicle of ‘objectness’.
Helena Hejman
doaj +1 more source

