Results 61 to 70 of about 291,863 (292)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Inscriptions: drawing, making, thinking [PDF]

open access: yes, 2010
‘Inscription: drawing, making, thinking’ brought together the work of David Conneam, Philip Eglin and Charlotte Hodes, it included drawings, ceramics, moving image and evidence of their working process.
Hodes, Charlotte
core  

Comforting sentences from the warming room at Inchcolm abbey [PDF]

open access: yes, 2012
A fragmentary inscription from the fifteenth century is reconstructed and its source identified, offering an insight into the use of one proverbial source of morally and spiritually encouraging sentences, and opening another little window on to the books ...
Davies, J.R., Sharpe, R., Taylor, S.
core   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

The Byzantine Army in 626–628 AD: Near East Frontier and Armenian Provinces

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки, 2018
Two aspects of the Byzantine military organization in 626–628 AD were considered: the role and status of Armenian ethnic units within the Byzantine army and the measures of Emperor Heraclius for reestablishment the Byzantine defense system in the Near ...
E.A. Mekhamadiev
doaj  

PRASASTI BANU RARA II

open access: yesBerkala Arkeologi, 1988
Pada tanggal 10 sampai dengan 24 Pebruari 1980, bersama-sama dengan beberapa orang teman dari Jakarta dan BaIi, penulis mendapat tugas melakukan penelitian beberapa lembar prasasti yang tersimpan di dalam Pura Pemrajan Rajapurana di Banjar Sangguhan dan ...
Sukarto Karto Atmodjo
doaj   +1 more source

A Hall For Hercules At Ostia And A Farewell To The Late Antique >Pagan Revival> [PDF]

open access: yes, 2010
In 1945, Herbert Bloch published an inscription from Ostia recording the restoration of a cellam Herc[ulis] in the late fourth century and suggested that it heralded the last pagan revival in the western Roman empire.
Boin, Douglas R.
core  

Ultrafast laser inscription of mid-IR directional couplers for stellar interferometry [PDF]

open access: yes, 2014
We report the ultrafast laser fabrication and mid-IR characterization (3.39 microns) of four-port evanescent field directional couplers. The couplers were fabricated in a commercial gallium lanthanum sulphide glass substrate using sub-picosecond laser ...
Arriola, Alexander   +4 more
core   +2 more sources

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy