Results 51 to 60 of about 287,996 (274)

Yang Liangyao's Mission of 785 to the Caliph of Baġdād: evidence of an early Sino-Arabic power alliance? [PDF]

open access: yes, 2015
The primary focus of this article is the information provided in a tomb stele (shendao zhi bei 神道之碑) of a Chinese eunuch, a certain Yang Liangyao 楊良瑤 (736–806), that will be comparatively analysed against the background of the political landscape under ...
Schottenhammer, Angela
core  

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

“Who of us has never traced light over these walls”?: The archaeology of Stanisław Grochowiak’s poems

open access: yesActa Universitatis Lodziensis. Folia Litteraria Polonica, 2020
Through a simple wall, a transparent element of everyday life, Stanisław Grochowiak’s poems enable one to uncover the existential concrete element, matter endowed with an amazing hypnagogic potential, a chronicle of ‘objectness’.
Helena Hejman
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Variations on the Author [PDF]

open access: yes, 2016
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship.
Sayad, Cecilia
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Pierres & inscriptions

open access: yes, 2020
Parmi les sources indiennes anciennes, qu’elles soient épigraphiques ou archéologiques, on peut souvent distinguer sources royales et non royales (ou locales), sources publiques et privées. Dans de nombreux cas, le royal semble avoir le statut d’archétype, inventé d’abord pour des usages royaux, puis adopté et adapté par des acteurs autres que royaux ...
openaire   +2 more sources

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Ultrafast laser inscription of mid-IR directional couplers for stellar interferometry [PDF]

open access: yes, 2014
We report the ultrafast laser fabrication and mid-IR characterization (3.39 microns) of four-port evanescent field directional couplers. The couplers were fabricated in a commercial gallium lanthanum sulphide glass substrate using sub-picosecond laser ...
Arriola, Alexander   +4 more
core   +2 more sources

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