Results 231 to 240 of about 617,921 (305)

Extended phenotype of phytoplasmas in eukaryotic systems: mechanisms and ecological implications. [PDF]

Front Plant Sci
Priyadharshini E, Sandhya M, Anand T, Angamuthu M, Murugan M, Tharmalingam N, Senthilraja G.   +6 more
europepmc   +1 more source

Microbial keystone taxa and metabolic signatures in centenarians regulate intestinal homeostasis during aging

iMeta, EarlyView.
Clostridium scindens and its metabolite indole‐3‐acetic acid (IAA) are identified as a keystone taxon and metabolic signature in centenarians. Clostridium scindens enhances microbial network stability and produces IAA via its own amidase (AMIE) and aldehyde dehydrogenase (ALDH), thus promoting intestinal homeostasis by activating the aryl hydrocarbon ...
Wei‐Chuan Lin, Cui Zhang, He‐Hua Lei, Zheng Cao, Xin Gao, Wen‐Kai Yu, Xin‐Zhi Li, Qing‐Wei Xiang, Zhi‐Wen Zhang, Shi‐Fu Pang, Wei‐Fei Luo, Deng‐Hui Xie, Li‐Min Zhang, Gang Chen   +13 more
wiley   +1 more source

Deep learning and attention mechanisms to identify key genes and their implications for the origin of insect wings. [PDF]

Sci Rep
Liu F, Cao Y, Qian S, Tong X, Liu J, Mao J, Li S, Li S, Zhao Y.   +8 more
europepmc   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

Interdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione, Ana Talamillo, Juan M. Falcón‐Pérez   +2 more
wiley   +1 more source

Streptomyces produce a diphtheria toxin-like exotoxin that targets insects. [PDF]

Nat Microbiol
Xu Y, Stubbendieck RM, Viswanatha R, Krč A, Baik LS, Suh WS, Hu Y, Wang H, Yin L, Mameli E, van der Meij A, Carlson JR, Doxey AC, Stenmark P, Perrimon N, Currie CR, Dong M.   +16 more
europepmc   +1 more source

Parental Exposure to Nanoplastics and Graphene Oxide Induces Transgenerational Toxicity in Caenorhabditis elegans

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental pollution by emerging contaminants such as nanoplastics (NPs) and graphene oxide (GO) represents a growing threat to global health and ecosystems. This study investigated the effects of parental exposure, both isolated and combined, to 100 μg/L NPs (polystyrene, spherical, 100 nm) and 100 mg/L GO, using Caenorhabditis elegans as ...
Gabriela Corrêa Soares, Larissa Müller, Suamy Machado Cruz, Andy Taipe Huisa, Danilo Roberto Carvalho Ferreira, Clascídia Aparecida Furtado, Juliane Ventura‐Lima   +6 more
wiley   +1 more source

The RNA helicase eIF4A as a novel target in insect cells to combat arboviral infections. [PDF]

PLoS One
Rehling T, Mentchen K, Konopka L, Obermann W, Weber F, Schmerer P, Schetelig MF, Grünweller A, Häcker I, Magari F.   +9 more
europepmc   +1 more source

Chlorfenapyr Induces Hepatotoxicity Associated With Oxidative Stress and Mitochondrial Dysfunction Involving Keap1/Nrf2 Signaling

Journal of Applied Toxicology, EarlyView.
ABSTRACT Chlorfenapyr (CHL) is a widely used pyrrole insecticide, but its hepatotoxic effects and underlying mechanisms remain incompletely understood. This study investigated the toxic effects of CHL on rat liver and BRL‐3A hepatocytes and explored the involvement of the Keap1/Nrf2 signaling pathway. Rats were administered CHL (10, 20, or 30 mg/kg) by
Dongquan Zhao, Jia Li, Cheng Li, Hua He, Lipu Deng   +4 more
wiley   +1 more source

Limited thermal tolerance in tropical insects and its genomic signature. [PDF]

Nature
Holzmann KL, Schmitzer T, Abels A, Čorkalo M, Mitesser O, Kortmann M, Alonso-Alonso P, Correa-Carmona Y, Pinos A, Yon F, Alvarado M, Forsyth A, Lopera-Toro A, Brehm G, Keller A, Otieno M, Steffan-Dewenter I, Peters MK.   +17 more
europepmc   +1 more source