Results 111 to 120 of about 447,355 (249)

Essential Role of COP9 Signalosome Subunit 5 (Csn5) in Insect Pathogenicity and Asexual Development of Beauveria bassiana [PDF]

, 2021
Ya‐Ni Mou, Kang Ren, Sen‐Miao Tong, Sheng‐Hua Ying, Ming‐Guang Feng   +4 more
openalex   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

Advanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva, Sara Duarte‐Silva, Pedro M. Martins, Beatriz Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Perez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana Fraga, James Noble, Carter Lantz, Niki Sepanj, Daniela Monteiro‐Fernandes, Sara Guerreiro, Andreia Neves‐Carvalho, Joana Pereira‐Sousa, Frank‐Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Annalisa Pastore, Elsa Sanchez‐Garcia, Gal Bitan, Ana Luísa Carvalho, Patrícia Maciel, Sandra Macedo‐Ribeiro   +28 more
wiley   +1 more source

Targeting TRAF6/IRF3 axis to inhibit NF-κB-p65 nuclear translocation enhances the chemosensitivity of 5-FU and reverses the proliferation of gastric cancer

Cell Death and Disease
Chemoresistance poses a significant clinical challenge in the treatment of gastric cancer (GC), while its underlying molecular mechanisms are still not fully understood.
Shitong Chen, Dong Zhang, Yi Du, Junbo Shi, Sikuan Gu, Xujun Zhou, Huijuan Yu, Feng Wang, Jinfei Chen, Hongjuan Cui   +9 more
doaj   +1 more source

Exploring the mechanisms of large local reactions to insect bites in patients with chronic lymphocytic leukaemia [PDF]

, 2016
Jamma Li, Giles Best, Stephen P. Mulligan, Suran L. Fernando   +3 more
openalex   +1 more source

Identification of PKN2 and MOB4 as Coordinators of Collective Cell Migration

Advanced Science, EarlyView.
Through a genetic screen, PKN2 and MOB4 are identified as two proteins regulating the healing of an epithelial model wound. PKN2 promotes collective cell migration by maintaining the cohesion of cell monolayers from their lateral junctions, whereas MOB4 restrains collective cell migration and provides a lamellipodial cue for front‐rear polarity in ...
Artem I. Fokin, Yueying Lin, Dmitry Y. Guschin, Hsiang‐Ying Chen, John James, Jie Yan, Pascal Silberzan, Alexis M. Gautreau   +7 more
wiley   +1 more source

Transcriptomic changes in the microsporidia proliferation and host responses in congenitally infected embryos and larvae

BMC Genomics
Congenital infection caused by vertical transmission of microsporidia N. bombycis can result in severe economic losses in the silkworm-rearing industry.
Zigang Shen, Zhuojun Ke, Qiong Yang, Samson Teweldeberhan Ghebremichael, Tangxin Li, Tian Li, Jie Chen, Xianzhi Meng, Heng Xiang, Chunfeng Li, Zeyang Zhou, Guoqing Pan, Ping Chen   +12 more
doaj   +1 more source

A survey of systems of grain storage and management of insect pests in stored grain in Kebbi state

, 2013
Iliyasu Mohammed Utono
openalex   +1 more source

Teleogryllus commodus Physicochemical raw data - Insects MDPI 2023

, 2023
Ahmad Bukhary Ahmad Khair
openalex   +1 more source

Efficient Light Harvesting and Water Retention Realized by Soybean Protein‐Based Microgels Embedded in Hybrid Sodium Alginate Hydrogels Containing Photocatalyst for Hydrogen Evolution

Advanced Science, EarlyView.
By incorporating SPN/SA microgels into SA hydrogels containing g‐C3N4/Pt nanosheets, highly efficient light absorption and superior water retention are achieved, thereby significantly enhancing hydrogen evolution efficiency. This is because microgels act as light scattering centers, enabling effective scattering of incident light and improving light ...
Jie Yu, Neng Hu, Weijia Wang, Lin Lei, Huiqing Fan, Peter Müller‐Buschbaum, Qi Zhong   +6 more
wiley   +1 more source

2‐line Ferrihydrite Enhance Microbial Synthesis of Plant Biostimulants in Composted Biosolid by Regulating Phyla Pseudomonadota and Actinomycetota

Advanced Science, EarlyView.
This study explores how iron and manganese oxides transform sewage sludge into plant biostimulants during composting. Non‐targeted identification reveals the main species of plant biostimulants. Metagenomic analysis reveals that 2‐line ferrihydrite specifically enriches microbial genes for biosynthesis, boosting plant‐growth promoters.
Yu Zhang, Ziwei Zhang, Zexu Chen, Boyuan Yang, Siying Cai, Jun Chen, Jianhua Guo, Weijun Zhang   +7 more
wiley   +1 more source