Results 121 to 130 of about 775,063 (321)

Protease‐Mediated Synthesis of Zein Nanofibrils: From Structural Elucidation to Functional Application

open access: yesAdvanced Science, EarlyView.
The globular shape and hydrophobicity of zein made it unsuitable to be processed in pure aqueous environment. Pepsin‐mediated hydrolysis converts zein into water‐soluble and fibril‐forming peptides with a bioconversion rate exceeding 70%, enabling the self‐assembly of amyloid‐like nanofibrils.
Mingqin Li   +8 more
wiley   +1 more source

Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT

open access: yesAdvanced Science, EarlyView.
Schematic diagram illustrating the mechanism of shortened lifespan in Thy 1‐C/EBPβ transgenic mice and intervention strategies. Briefly, C/EBPβ/AEP escalation in the aging brain triggers NAMPT fragmentation and NAD+ depletion. Knockout of AEP from Thy 1‐C/EBPβ Tg/Tg mice ameliorates cognitive impairments and elongates the lifespan.
Bowei Li   +8 more
wiley   +1 more source

Alternative splicing of the FLOWERING LOCUS C-like gene MaMADS33 is associated with endodormancy in mulberry

open access: yesForestry Research
Alternative splicing (AS) is an important post-transcriptional process that generates multiple mRNA isoforms. FLOWERING LOCUS C (FLC) is a pivotal gene in both the vernalization and autonomous pathways of flowering plants, and MaMADS33 is one of the FLC ...
Yiwei Luo   +5 more
doaj   +1 more source

Basic offspring number and robust feedback design for the biological control of vectors by sterile insect release technique [PDF]

open access: yesarXiv
Sterile Insect Technique (SIT) is a promising control method against insect pests and insect vectors. It consists in releasing males previously sterilized in laboratory, in order to reduce or eliminate a specific wild population. We study in this paper the implementation by feedback control of SIT-based elimination campaign of Aedes mosquitoes.
arxiv  

Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA

open access: yesAdvanced Science, EarlyView.
Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin   +9 more
wiley   +1 more source

An Insect Salivary Sheath Protein Triggers Plant Resistance to Insects and Pathogens as a Conserved HAMP

open access: yesAdvanced Science, EarlyView.
The salivary sheath protein myosin from SBPH is critical for the formation of the salivary sheath and feeding. However, myosin functions as a HAMP and triggered plant BAK1‐mediated PTI responses, which include the activation of calcium signaling pathways, MAPK phosphorylation, ROS bursts, and cell death, thereby triggering JA pathway.
Liangxuan Qi   +12 more
wiley   +1 more source

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