Results 71 to 80 of about 1,001,632 (316)
Meniere's disease treated by grommet insertion [PDF]
, 2019 INTRODUCTION: Menière’s disease (MD) is an uncommon cause of sudden profound vertigo. A variety of medical and surgical treatments have been used to manage this condition.
Kanegaonkar, R. +3 more
core
Translocation and insertion of precursor proteins into isolated outer membranes of mitochondria [PDF]
, 1993 Nuclear-encoded proteins destined for mitochondria must cross the outer or both outer and inner membranes to reach their final sub- mitochondrial locations. While the inner membrane can translocate preproteins by itself, it is not known whether the outer
W Neupert +5 more
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Mechanism of Sec61-mediated insertion of proteins into the endoplasmic reticulum membrane [PDF]
, 2010 In eukaryotic cells, hydrophobic signal sequences of newly synthesized secretory and membrane proteins target them to the Sec61 translocon in the endoplasmic reticulum (ER) membrane.
Kocik, Lucyna
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Hiatus of Vowels and Resolving Them in Central Kurdish [PDF]
مطالعات زبانها و گویشهای غرب ایران, 2019 In this article, the authors have studied the phenomenon of hiatus of vowels and some approaches to resolve it in central Kurdish through descriptive-analytical method and have analyzed collected data in the framework of optimality theory.
Mehran Ahmadi +2 more
doaj
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Insertion of EGFP into the replicase gene of Semliki Forest virus results in a novel, genetically stable marker virus [PDF]
, 2007 Alphavirus-based vector and replicon systems have been extensively used experimentally and are likely to be used in human and animal medicine. Whilst marker genes can be inserted easily under the control of a duplicated subgenomic promoter, these ...
Fazakerley, John K +11 more
core +1 more source
Reactivity of Mononuclear and Dinuclear Gold(I) Amidinate Complexes with CS2 and CsBr3
Inorganics, 2014 To probe the reactivity of gold-nitrogen bonds, we have examined the insertion chemistry with carbon disulfide (CS2) as well as oxidation with cesium tribromide (CsBr3) with Au(I) amidinate complexes. The reaction of Ph3PAuCl with Na[(2,6-Me2C6H3N)2C(H)
Andrew C. Lane +3 more
doaj +1 more source
Construction of Small-Insert and Large-Insert Metagenomic Libraries
, 2010 The vast majority of the Earth's biological diversity is hidden in uncultured and yet uncharacterized microbial genomes. The construction of metagenomic libraries is a cultivation-independent molecular approach to assess this unexplored genetic reservoir.
Simon, Carola +3 more
openaire +5 more sources