Results 211 to 220 of about 4,048,456 (298)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Characterization of a Mycobacterium tuberculosis insertion sequence, IS6110, and its application in diagnosis

Journal of Clinical Microbiology, 1990
D. Thierry, A. Brisson-Noël, V. Vincent-Lévy-Frébault, Son Hoang Nguyen, J. Guesdon, B. Gicquel   +5 more
semanticscholar   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Genome Sequence of Lactobacillus helveticus, an Organism Distinguished by Selective Gene Loss and Insertion Sequence Element Expansion

Journal of Bacteriology, 2007
M. Callanan, Paweł Kaleta, J. O'callaghan, O. O’Sullivan, K. Jordan, O. McAuliffe, A. Sangrador-Vegas, Lydia Slattery, Geraldd F Fitzgerald, T. Beresford, R. P. Ross   +10 more
semanticscholar   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Plasmids promote antimicrobial resistance through Insertion Sequence-mediated gene inactivation

Sastre-Dominguez J, Rodera-Fernandez P, DelaFuente J, Martínez-González S, Quesada S, Valencoso-Requena M, Calvo-Villamañan A, Costas C, Fuentes-Hernández A, Santos-Lopez A, San Millan A.   +10 more
europepmc   +1 more source

Insertion sequence elements-mediated structural variations in bacterial genomes. [PDF]

Mob DNA, 2018
Nzabarushimana E, Tang H.
europepmc   +1 more source

Harmonizing the Pyrene and Ether Groups in Covalent Triazine Polymers for Highly Effective H2O2 Photosynthesis via One‐Step Two‐Electron Oxygen Reduction

Advanced Functional Materials, EarlyView.
The pyrene and ether groups are incorporated into the covalent triazine polymer (CTP) structure. The synergistic effect of the two functional groups endows CTP with better electron transfer, light absorption, and oxygen activation properties. An impressive apparent quantum yield (13.2% @420 nm) and a remarkable solar‐to‐chemical conversion efficiency ...
Chong Wang, Jinliang Lv, Yichun Lu, Hanfeng Ye, Xuan Zhang, Leonardo Cancellara, Nadezda Tarakina, Jiande Lin, Xin Gao, Oleksandr Savateev, Jiajia Cheng   +10 more
wiley   +1 more source

Transposition of an insertion sequence, ISTth7, in the genome of the extreme thermophile Thermus thermophilus HB8.

FEMS Microbiology Letters, 2008
S. T. Gregory, A. E. Dahlberg
semanticscholar   +1 more source

Crack‐Growing Interlayer Design for Deep Crack Propagation and Ultrahigh Sensitivity Strain Sensing

Advanced Functional Materials, EarlyView.
A crack‐growing semi‐cured polyimide interlayer enabling deep cracks for ultrahigh sensitivity in low‐strain regimes is presented. The sensor achieves a gauge factor of 100 000 at 2% strain and detects subtle deformations such as nasal breathing, highlighting potential for minimally obstructive biomedical and micromechanical sensing applications ...
Minho Kim, Taewi Kim, Jieun Park, Insic Hong, Myungrae Hong, Seonggyeong Park, Beomjin Kim, Sehyuk Ahn, Siwoo Jang, Seungyong Han, Je‐Sung Koh, Daeshik Kang   +11 more
wiley   +1 more source