Results 101 to 110 of about 8,338,005 (303)

Becoming the Community's Foundation: Insight and Change in New Haven [PDF]

, 2003
FSG helped the Community Foundation for Greater New Haven to develop a new donor development strategy based on an understanding of three critical questions: What motivates different segments of donors?
John Kania, Matthew Clark
core  

An insight into polarization states of solid-state organic lasers

, 2012
The polarization states of lasers are crucial issues both for practical applications and fundamental research. In general, they depend in a combined manner on the properties of the gain material and on the structure of the electromagnetic modes.
A. Brosseau, A. Matsko, B. Valeur, C. Lafargue, C. Ulysse, G. Clavier, I. Gozhyk, J. R. Lakowicz, J. Zyss, J.-F. Audibert, M. Dvorko, M. Lebental, O. Svelto, R. Méallet-Renault, R. Pansu, S. Chénais, S. Forget, S. Lozenko, V. Tsvirkun   +18 more
core   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Comparison of intraoral and extraoral scanners on the accuracy of digital model articulation [PDF]

, 2017
Introduction: Orthodontists increasingly rely on digital models in clinical practice. The ability of modern scanners to articulate digital models must be scientifically evaluated.
Porter, Jason L
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An insight into gut microbiota and its functionalities

Cellular and Molecular Life Sciences, 2018
A. Adak, M. Khan
semanticscholar   +1 more source

Constraints on the shallow elastic and anelastic structure of Mars from InSight seismic data

Nature Geoscience, 2020
P. Lognonné, P. Lognonné, W. Banerdt, W. Pike, D. Giardini, U. Christensen, R. Garcia, T. Kawamura, S. Kedar, B. Knapmeyer‐Endrun, L. Margerin, F. Nimmo, M. Panning, B. Tauzin, John‐Robert Scholz, Daniele Antonangeli, S. Barkaoui, É. Beucler, F. Bissig, N. Brinkman, M. Calvet, S. Ceylan, C. Charalambous, P. Davis, M. Driel, M. Drilleau, L. Fayon, R. Joshi, B. Kenda, Amir Khan, Amir Khan, M. Knapmeyer, V. Lekić, J. McClean, D. Mimoun, N. Murdoch, Lu Pan, C. Perrin, B. Pinot, L. Pou, S. Menina, Sebastien Rodriguez, Sebastien Rodriguez, C. Schmelzbach, N. Schmerr, D. Sollberger, A. Spiga, A. Spiga, S. Stähler, A. Stott, É. Stutzmann, S. Tharimena, R. Widmer-Schnidrig, Fredrik Andersson, V. Ansan, C. Beghein, M. Böse, E. Bozdağ, J. Clinton, I. Daubar, P. Delage, N. Fuji, M. Golombek, M. Grott, A. Horleston, K. Hurst, J. Irving, A. Jacob, J. Knollenberg, S. Krasner, C. Krause, R. Lorenz, C. Michaut, C. Michaut, R. Myhill, T. Nissen‐Meyer, J. Pierick, A. Plesa, C. Quantin-Nataf, J. Robertsson, L. Rochas, M. Schimmel, S. Smrekar, T. Spohn, N. Teanby, J. Tromp, J. Vallade, N. Verdier, C. Vrettos, R. Weber, D. Banfield, E. Barrett, M. Bierwirth, S. Calcutt, N. Compaire, C. L. Johnson, C. L. Johnson, D. Mance, F. Euchner, L. Kerjean, G. Mainsant, A. Mocquet, J. Manfredi, G. Pont, P. Laudet, T. Nebut, S. D. Raucourt, O. Robert, C. T. Russell, A. Sylvestre-baron, S. Tillier, T. Warren, M. Wieczorek, C. Yana, P. Zweifel   +114 more
semanticscholar   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Insight Into Insight in Psychotherapy [PDF]

American Journal of Psychiatry, 2018
openaire   +2 more sources