Results 121 to 130 of about 2,234,074 (317)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Dir. Orson Welles's Citizen Kane
, 2023 Insight Text Guides take students into the deeper layers of meaning in a range of popular novels, plays, films, short-story collections and nonfiction texts. They are designed to develop detailed knowledge, in-depth understanding and genuine insight into
Barnes, Diana
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Charmaine Papertalk Green & John Kinsella's False Claims of Colonial Thieves
, 2023 Insight Text Guides take students into the deeper layers of meaning in a range of popular novels, plays, films, short-story collections and nonfiction texts. They are designed to develop detailed knowledge, in-depth understanding and genuine insight into
Barnes, Diana
core
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
, 2023 Insight Text Guides take students into the deeper layers of meaning in a range of popular novels, plays, films, short-story collections and nonfiction texts. They are designed to develop detailed knowledge, in-depth understanding and genuine insight into
Barnes, Diana
core
BMC Medical Research MethodologyBackground and objectives The National Institute for Health and Care Excellence (England’s health technology assessment body) recommend the use of the average treatment effect (ATE) as an estimand for economic evaluations.
Danilo Di Maio +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Dir. Sarah Polley's Stories we tell
, 2023 Insight Text Guides take students into the deeper layers of meaning in a range of popular novels, plays, films, short-story collections and nonfiction texts. They are designed to develop detailed knowledge, in-depth understanding and genuine insight into
Barnes, Diana
core
Patchy signals: capturing women’s voices in mobile phone surveys of rural India
BMJ Global Health, 2021 Skye Hersh +3 more
doaj +1 more source