Results 41 to 50 of about 1,430,196 (268)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Magnetic particle imaging tracers for human applications: preclinical in vivo evaluation of Magtrace, Resotran, and FerroTrace

npj Imaging
Sentinel lymph node (SLN) mapping is essential for cancer staging and treatment planning. Superparamagnetic iron oxides (SPIOs) are used for magnetic SLN localization in breast cancer and are being explored in cancers with complex lymphatic drainage ...
Olivia C. Sehl, Nitara Fernando, Petrina Kim, A. Rahman Mohtasebzadeh, Toby Sanders, Kelvin Guo, Benjamin Fellows, Michael D. Alvarado, Benjamin Thierry, Marcela Weyhmiller, Joan M. Greve, Stephen Y. Lai, Patrick W. Goodwill, Paula J. Foster   +13 more
doaj   +1 more source

CARACTERIZACIÓN TEÓRICA DE PÉPTIDOS DE ALTA UNIÓN DE EBA-181 MEDIANTE LA APLICACIÓN DE LA TEORÍA DE LA PROBABILIDAD Y LA ENTROPÍA

Revista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturales, 2023
El antígeno EBA-181 del Plasmodium falciparum se une al glóbulo rojo sugiriendo un papel en la invasión por parte del merozoito. Se aplicó una metodología previamente desarrollada con base en la probabilidad y la entropía, a la caracterización de ...
Javier Rodríguez, Signed Prieto, Pedro Bernal, Catalina Correa, Sarith Vitery, Jessica Mora, Diego Tapia, Fredy López   +7 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Digital amnesia and the future tourist [PDF]

Journal of Tourism Futures, 2017
Purpose – The purpose of this paper is to examine the phenomenon of digital amnesia and its influence on the future tourist. Design/methodology/approach – A trend paper based on environmental scanning and speculative future analysis.
Chris Greenwood, Matthew Quinn
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Diagnóstico matemático de la monitoría fetal con la Ley de Zipf-Mandelbrot y la teoría de los sistemas dinámicos aplicados a la fisiología cardiaca

Revista Colombiana de Obstetricia y Ginecología, 2006
Objetivo: desarrollar un diagnóstico matemático de la monitoría fetal a partir de la aplicación de la ley de Zipf-Mandelbrot y las concepciones de salud y enfermedad de los sistemas dinámicos a la aparición de Componentes Dinámicos del Sistema (CDS) en ...
Rodríguez Javier, Prieto Signed, Liliana Ortiz, Alejandro Bautista, Luisa Álvarez, Catalina Correa, Nicolás Avilán   +6 more
doaj  

Mortality Predictors for Adult Patients with Mild-to-Moderate Traumatic Brain Injury: A Literature Review

Neurology International
Traumatic brain injuries (TBIs) represent a significant public health concern, with mild-to-moderate cases comprising a substantial portion of incidents. Understanding the predictors of mortality among adult patients with mild-to-moderate TBIs is crucial
Ansam Eghzawi, Alameen Alsabbah, Shatha Gharaibeh, Iktimal Alwan, Abeer Gharaibeh, Anita V. Goyal   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source