Results 111 to 120 of about 3,165,406 (373)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Conditional Random Field Approach Combining FFT Filtering and Co-Kriging for Reliability Assessment of Slopes

open access: yesApplied Sciences
Conventional unconditional random field (URF) models were shown to neglect in-situ monitoring data and thus misrepresent real slope stability. To address this, a conditional random field (CRF) generator was proposed, in which Fast Fourier Transform (FFT)
Xin Dong   +7 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Numerical Shear Tests on the Scale Effect of Rock Joints under CNL and CND Conditions

open access: yesAdvances in Civil Engineering, 2020
The scale effect of rock joint shear behavior is an important subject in the field of rock mechanics. There is yet a lack of consensus regarding whether the shear strength of rock joints increases, decreases, or remains unchanged as the joint size ...
Xige Liu, Wancheng Zhu, Lankun Li
doaj   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

open access: yesMolecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo   +6 more
wiley   +1 more source

Chronic Ankle Instability Leads to Lower Extremity Kinematic Changes During Landing Tasks: A Systematic Review

open access: yesInternational Journal of Exercise Science, 2019
Ankle and knee injuries are two of the most common injuries. It has been shown that ankle sprains can lead to chronic ankle instability thereby affecting the function of the ankle.
Aaron Theisen, James Day
semanticscholar   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

Study on Rockburst Nucleation Process of Deep-Buried Tunnels Based on Microseismic Monitoring

open access: yesShock and Vibration, 2015
The objective of this study was to investigate the rockburst nucleation process and provide a theoretical basis for its prediction. A microseismic monitoring system was established in deep tunnels at Jinping II Hydropower Station.
Qun Yu   +4 more
doaj   +1 more source

The instability of studies of instability [PDF]

open access: yesJournal of Evolutionary Biology, 1997
Michael C. Whitlock, Kevin Fowler
openaire   +2 more sources

Not just a by‐product: circular DNA molecules derived from V(D)J recombination are linked to worse prognosis in B‐cell leukemia

open access: yesMolecular Oncology, EarlyView.
Gao et al. report that circular DNA molecules created as by‐products of V(D)J recombination during lymphocyte maturation (ESCs) can replicate and be retained for much longer than previously thought in healthy cells. In BCP‐ALL cells, increased ESC abundance correlates with a greater chance of relapse likely mediated by their ability to induce genome ...
Davide Pradella, Andrea Ventura
wiley   +1 more source

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