Results 51 to 60 of about 2,390,832 (281)

Stylolite fractal characteristics and the influence of stylolite on strength of limestone

工程科学学报, 2017
To study the fractal characteristics of stylolite and its influence on the strength of limestone, the fractal dimension of horizontal stylolite and vertical stylolite was analyzed using the power spectral density method and the digital image box ...
LU Jian-tao, XU Tao, Patrick Baud, YANG Tian-hong, ZHOU Guang-lei, CHEN Chong-feng   +5 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

An in silico analysis identifies drugs potentially modulating the cytokine storm triggered by SARS-CoV-2 infection

Scientific Reports, 2022
The ongoing COVID-19 pandemic is one of the biggest health challenges of recent decades. Among the causes of mortality triggered by SARS-CoV-2 infection, the development of an inflammatory “cytokine storm” (CS) plays a determinant role.
Laura Sanchez-Burgos, Gonzalo Gómez-López, Fátima Al-Shahrour, Oscar Fernandez-Capetillo   +3 more
doaj   +1 more source

The subcritical baroclinic instability in local accretion disc models

, 2010
(abridged) Aims: We present new results exhibiting a subcritical baroclinic instability (SBI) in local shearing box models. We describe the 2D and 3D behaviour of this instability using numerical simulations and we present a simple analytical model ...
Barge, Barranco, Chagelishvili, de Val-Borro, de Val-Borro, Fricke, Fromang, Fromang, Fromang, G. Lesur, Goldreich, Hawley, Hawley, Heinemann, Heinemann, J. C. B. Papaloizou, Ji, Johnson, Johnson, Johnson, Kida, Klahr, Klahr, Kley, Lesur, Lesur, Lesur, Lovelace, Mizerski, Papaloizou, Petersen, Petersen, Regev, Spiegel, Umurhan, von Weizsäcker, Ziegler   +36 more
core   +3 more sources

The blue-edge problem of the V1093 Her instability strip revisited using evolutionary models with atomic diffusion [PDF]

, 2014
We have computed a new grid of evolutionary subdwarf B star (sdB) models from the start of central He burning, taking into account atomic diffusion due to radiative levitation, gravitational settling, concentration diffusion, and thermal diffusion.
Aerts, C., Bloemen, S., Degroote, P., Dupret, M. A., Hu, Haili, Müller-Ringat, E., Rauch, T., Østensen, R. H.   +7 more
core   +4 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Vaccines against candidiasis: Status, challenges and emerging opportunity

Frontiers in Cellular and Infection Microbiology, 2022
Candidiasis is a mycosis caused by opportunistic Candida species. The occurrence of fungal infections has considerably increased in the last few years primarily due to an increase in the number of immune-suppressed individuals.
Satya Ranjan Sahu, Satya Ranjan Sahu, Swagata Bose, Swagata Bose, Manish Singh, Premlata Kumari, Premlata Kumari, Abinash Dutta, Bhabasha Gyanadeep Utkalaja, Bhabasha Gyanadeep Utkalaja, Shraddheya Kumar Patel, Shraddheya Kumar Patel, Narottam Acharya   +12 more
doaj   +1 more source

Simulations of two-planet systems through all phases of stellar evolution: implications for the instability boundary and white dwarf pollution [PDF]

, 2013
Exoplanets have been observed at many stages of their host star's life, including the main sequence (MS), subgiant and red giant branch stages. Also, polluted white dwarfs (WDs) likely represent dynamically active systems at late times.
Bonsor, Amy, Mustill, Alexander J., Veras, Dimitri, Wyatt, Mark C.   +3 more
core   +2 more sources