Results 81 to 90 of about 1,282,741 (306)

The Growth Effects of Institutional Instability [PDF]

open access: yes
Both institutional quality and institutional stability have been argued to stimulate economic growth. But to improve institutional quality, a country must endure a period of institutional change, which implies at least a little and possibly a lot of ...
Berggren, Niclas   +2 more
core  

Conditional Random Field Approach Combining FFT Filtering and Co-Kriging for Reliability Assessment of Slopes

open access: yesApplied Sciences
Conventional unconditional random field (URF) models were shown to neglect in-situ monitoring data and thus misrepresent real slope stability. To address this, a conditional random field (CRF) generator was proposed, in which Fast Fourier Transform (FFT)
Xin Dong   +7 more
doaj   +1 more source

Numerical Shear Tests on the Scale Effect of Rock Joints under CNL and CND Conditions

open access: yesAdvances in Civil Engineering, 2020
The scale effect of rock joint shear behavior is an important subject in the field of rock mechanics. There is yet a lack of consensus regarding whether the shear strength of rock joints increases, decreases, or remains unchanged as the joint size ...
Xige Liu, Wancheng Zhu, Lankun Li
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Global behaviour corresponding to the absolute instability of the rotating-disc boundary layer [PDF]

open access: yes, 2003
A study is carried out of the linear global behaviour corresponding to the absolute instability of the rotating-disc boundary layer. It is based on direct numerical simulations of the complete linearized Navier–Stokes equations obtained with the novel ...
Carpenter, P. W.   +4 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Instability in Andhra Pradesh Agriculture — A Disaggregate Analysis [PDF]

open access: yes
Instability in farm production is causing serious shocks to supply and farm income and there is a growing concern about increased volatility in farm production, prices and farm income. The study has estimated instability in three major crops before (1981-
Chand, Ramesh, Raju, S.S.
core  

A novel transfer learning-enhanced BiLSTM-DCNN architecture for mine microseismic signal identification with small data set

open access: yesGeomechanics and Geophysics for Geo-Energy and Geo-Resources
The underground mining environment generates highly heterogeneous microseismic (MS) signals, whose accurate identification is crucial for source localization and failure mechanism analysis. Limited data in the early monitoring stages restrict recognition
Yong Zhao   +5 more
doaj   +1 more source

Experimental Investigation of Flow Domain Division in Beds Packed with Different Sized Particles

open access: yesEnergies, 2017
Seepage in a medium packed with particles of variable granular size can be seen in many fields of engineering applications. Due to the relative complex spatial aspect of pore geometry, there are notable differences in the critical parameters of flow ...
Xin Yang   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy