Results 91 to 100 of about 408,673 (331)
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Calculation and Analysis of Meshing Stiffness of Helical Gear Considering Installation Error
The analysis calculation of meshing stiffness of helical gear is the basis for the study of gear dynamics. According to the gear meshing principle and coordinate transformation theory the finite element model of helical gear meshing with the installation
Liu Baoshan, Du Qungui, Wen Qi
doaj
Air data position-error calibration using state reconstruction techniques [PDF]
During the highly maneuverable aircraft technology (HiMAT) flight test program recently completed at NASA Ames Research Center's Dryden Flight Research Facility, numerous problems were experienced in airspeed calibration.
Ehernberger, L. J. +2 more
core +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic +6 more
wiley +1 more source
Contact Analysis of Cylindrical Helical Gear Considering the Hob Installation Error
The high precision gear processing must consider the influence of machining error on the meshing quality,based on the basic principle of the contact analysis of helical gear,the simulation of involute helical gear is realized by using the Matlab software,
Zhang Rui +5 more
doaj
Analysis of the Modification Sensitivity of Herringbone Gear
In order to improve the applicability of herringbone gear modification results, it is necessary to analyze the sensitivity of gear surface modification parameters.
Yong Zhao +5 more
doaj
Frailty Exacerbates Disability in Progressive Multiple Sclerosis
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks +10 more
wiley +1 more source
US-LHC Magnet Database and conventions [PDF]
The US-LHC Magnet Database is designed for production-magnet quality assurance, field and alignment error impact analysis, cryostat assembly assistance, and ring installation assistance.
Bottura, L +7 more
core
Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew +11 more
wiley +1 more source

