Results 31 to 40 of about 39,954 (258)

Human errors. A taxonomy for describing human malfunction in industrial installations [PDF]

Journal of Occupational Accidents, 1982
This paper describes the definition and the characteristics of human errors. Different types of human behavior are classified, and their relation to different error mechanisms are analyzed. The effect of conditioning factors related to affective, motivating aspects of the work situation as well as physiological factors are also taken into consideration.
openaire   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Analysis and Compensation of Installation Errors for Rotating Semi-Strapdown Inertial Navigation System

IEEE Access, 2019
The rotation semi-strapdown inertial navigation system (RSSINS) provides a new solution for the high-precision measurement of high-spinning projectile flight parameters.
Jiayu Zhang, Jie Li, Yugang Huang, Chenjun Hu, Kaiqiang Feng, Xiaokai Wei   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Effect of Installation Errors of Helical Gear on Bearing Capacity

, 2023
Broken tooth roots due to mounting errors in helical gears at high speeds and heavy loads are a common problem in steel mills. Based on the contact characteristics of helical gears, this paper uses the finite element method to simulate the bending stress at the root of the pinion gear and the contact stress at the tooth surface under two cases of ...
Luan, Heng, Shu, Xiantao, Wang, Jiabing
openaire   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

A Method for the Installation Measurement and Alignment of a Mirror Unit in the Solar Dish Concentrator

Applied Sciences, 2020
The mirror unit installation error of the solar parabolic dish concentrator can adversely affect its optical performance causing optical intercept losses and hot spots on the absorber surface, which in turn affect safety.
Jian Yan, Youduo Peng, Duzhong Nie
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Vibration Characterization of Ship Propulsion System Including Stern-Bearing Installation Errors

Journal of Marine Science and Engineering
During the operation and service of a ship, its power system will affect the stability, reliability, and safety of the ship’s power system and the ship’s vitality if there are typical problems, such as unstable operation and vibration of the shaft system.
Jianhua Zhou, Shidong Fan, Hanhua Zhu, Yulei Zhu, Hailong Weng, Junlang Yuan, Taiwei Yang   +6 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source