Results 51 to 60 of about 39,850 (259)

Research on Transmission Error of Hypoid Gear based on Real Tooth Surface

Jixie chuandong, 2022
Aiming at the inconsistency evaluation standards caused by using the gear designed by theory for simulation and using the gear produced by actual production for roll inspection certificate test，by using the NURBS surface fitting method，the real tooth ...
Yimin Mo, Renjie Mo, Qiming Li, Jie Liu, Junjian Yang, Yecai Huang   +5 more
doaj  

Research on Eccentric Error Compensation of Aviation Gear Grinding Installation

Hangkong gongcheng jinzhan, 2018
There is eccentric error between the geometric center of the gear blank and the axis of the rotary table during the gear grinding process. The machining precision of grinding tooth accuracy is reduced.
Wang Peng, Wang Ying, Wang Ding, Tian Ying   +3 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Features of Determination of an Error of Installation as a Component of Machining Allowance

Visnyk of Vinnytsia Politechnical Institute, 2020
One of the important tasks of designing manufacturing processes for manufacturing parts is to designate optimal allowances for machining, since an unjustified increase in allowances leads to significant metal losses, increases the complexity of machining, and the appointment of unjustifiably small allowances may not ensure the removal of defective ...
O. V. Deribo, Zh. P. Dusaniuk
openaire   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

The bearing parallel misalignment running model–based machine tool spindle thermal error analysis

Advances in Mechanical Engineering, 2018
As a key component of the machine tool spindle, bearing has critical influences on the spindle thermal error. In particular, the installation errors of bearing have considerable effects upon the spindle thermal error by altering the bearings’ internal ...
Yanfang Dong, Zude Zhou, Lihai Chen
doaj   +1 more source

A New Method of Angle Measurement Error Analysis of Rotary Encoders

Applied Sciences, 2019
In this article, a method of error source analysis and detection to improve the angle measurement accuracy of rotary encoders in precision measuring instruments is proposed.
Hua-Kun Jia, Lian-Dong Yu, Hui-Ning Zhao, Yi-Zhou Jiang   +3 more
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Calculation and Analysis of Meshing Stiffness of Helical Gear Considering Installation Error

Jixie chuandong, 2017
The analysis calculation of meshing stiffness of helical gear is the basis for the study of gear dynamics. According to the gear meshing principle and coordinate transformation theory the finite element model of helical gear meshing with the installation
Liu Baoshan, Du Qungui, Wen Qi
doaj