Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Calibration and compensation methods of installation error of electronic compass
Installation error angle is one of the factors that affect the accuracy of electronic compass used for geomagnetic navigation.To solve this problem,the calibration and compensation methods for installation error angle are studied.By analyzing the ...
FAN Cheng-ye +6 more
doaj
Research on Transmission Error of Hypoid Gear based on Real Tooth Surface
Aiming at the inconsistency evaluation standards caused by using the gear designed by theory for simulation and using the gear produced by actual production for roll inspection certificate test,by using the NURBS surface fitting method,the real tooth ...
Yimin Mo +5 more
doaj
Research on Eccentric Error Compensation of Aviation Gear Grinding Installation
There is eccentric error between the geometric center of the gear blank and the axis of the rotary table during the gear grinding process. The machining precision of grinding tooth accuracy is reduced.
Wang Peng +3 more
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Ndithunuke ndizophola 2021’ installation
1. Ndithunuke ndizophola 2021’ installation • 10m x 10m slopping octagon labyrinth 10x10 presenting my life journey with animation of cancer healing experience. • Mayenzeke Intando Yakho Thixo Nkosi yenyaniso (stop frame animation).
Mpako, Nombeko
core
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Error report for Wessel (2018)
DECISION AND RECOMMENDATION Wessel (2018) “Prepotent motor activity and inhibitory control demands in different variants of the go/no-go paradigm” was determined to contain Minor Errors. That is, errors that have the benefit of being detectable thanks to
ERROR
core +1 more source
The bearing parallel misalignment running model–based machine tool spindle thermal error analysis
As a key component of the machine tool spindle, bearing has critical influences on the spindle thermal error. In particular, the installation errors of bearing have considerable effects upon the spindle thermal error by altering the bearings’ internal ...
Yanfang Dong, Zude Zhou, Lihai Chen
doaj +1 more source

