Results 41 to 50 of about 1,963,870 (281)
Changes in Lateral Stress During Slurry Trench Wall Installation. [PDF]
, 1996 PhDThe thesis is concerned with the effects of slurry trenching (diaphragm wall installation) in an overconsolidated clay, with particular emphasis on the changes in lateral stress which occur. A review of the literature on diaphragm wall installation
Page, Jonathan
core +4 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
IEEE Access, 2019 The rotation semi-strapdown inertial navigation system (RSSINS) provides a new solution for the high-precision measurement of high-spinning projectile flight parameters.
Jiayu Zhang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Applied SciencesLocal installation errors in stern-tube bearings can substantially affect shaft alignment, yet conventional calculations often represent these errors only as nominal support displacements.
Taiwei Yang +5 more
doaj +1 more source
Applied Sciences, 2020 The mirror unit installation error of the solar parabolic dish concentrator can adversely affect its optical performance causing optical intercept losses and hot spots on the absorber surface, which in turn affect safety.
Jian Yan, Youduo Peng, Duzhong Nie
doaj +1 more source
Features of Determination of an Error of Installation as a Component of Machining Allowance
Visnyk of Vinnytsia Politechnical Institute, 2020 One of the important tasks of designing manufacturing processes for manufacturing parts is to designate optimal allowances for machining, since an unjustified increase in allowances leads to significant metal losses, increases the complexity of machining, and the appointment of unjustifiably small allowances may not ensure the removal of defective ...
O. V. Deribo, Zh. P. Dusaniuk
openaire +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Vibration Characterization of Ship Propulsion System Including Stern-Bearing Installation Errors
Journal of Marine Science and EngineeringDuring the operation and service of a ship, its power system will affect the stability, reliability, and safety of the ship’s power system and the ship’s vitality if there are typical problems, such as unstable operation and vibration of the shaft system.
Jianhua Zhou +6 more
doaj +1 more source