Results 61 to 70 of about 26,113,156 (202)

ELABORATION OF THE MODEL OF INNOVATIVE MANAGEMENT OF EDUCATIONAL PROCESS INTENDED FOR ADAPTATION TO THE CHANGES IN THE EXTERNAL INSTITUTIONAL ENVIRONMENT

open access: yesRussian Journal of Economics and Law, 2012
The work discusses the requirements to the modern educational process and its features. The authors propose and ground the additional set of competences necessary for the students to ensure their competitiveness in the modern labour market.
L. V. Vorontsova, T. V. Kramin
doaj  

INSTITUTIONAL DEVELOPMENT OF VOLUNTEER MOVEMENT IN RUSSIA: METHODOLOGICAL APPROACHES AND EVOLUTION STAGES

open access: yesВестник Северо-Кавказского федерального университета, 2022
The author focuses on the process of institutionalization of the volunteer movement in the North Caucasus. There is substantiation provided to the use of institutional and structure-functional approaches to studying volunteer movement in the regional ...
Aleksey V. Shapovalov
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

INSTITUTIONAL APPROACH AS THE BASIS FOR THESYSTEM OF THE COMPANY COST MANAGEMENT

open access: yesRussian Journal of Economics and Law, 2007
The article analyzes the peculiarities of application of the transactional costs and agent relations theories in the practice of company cost management. The author defines the role of interests and corporate social responsibility theory in the formation
T. V. Kramin
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Institutional matrices and institutional changes [PDF]

open access: yes
This article represents a paper for the 5th International Symposium on Evolutionary Economics “Economic Transformation and Evolutionary Theory of J. Schumpeter” (Pushchino, Moscow region, Russia, 25-27 September, 2003).
Kirdina, Svetlana
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

An Institutional Approach to the Decarbonization of the Economy and the Transition to Clean Energy Based on EnergyTech

open access: yesFrontiers in Energy Research, 2022
Yuliya V. Chutcheva   +4 more
doaj   +1 more source

A New Institutional Approach of Resource Use Conflicts: The Case of Poitou-Charentes [PDF]

open access: yes
New Institutional Economics, based on the Coasean comparative approach, offers a highly useful framework for research on environmental problems. We propose a tentative analytic framework for environmental problems and we try its heuristic power by first ...
Ornella Boutry
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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