Results 91 to 100 of about 2,196,057 (314)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Redress and civil litigation report [PDF]
, 2015 The Royal Commission has examined the extent to which ‘justice for victims’ of institutional child abuse has been, or can be, achieved through previous and current redress processes and civil litigation systems.
Royal Commission into Institutional Responses to Child Sexual Abuse
core
Work environments and staff responses to work environments in institutional long-term care.
, 2009 Background: Structures and processes of care such as work environments and care provider responses to work environments have been shown to influence organizational outcomes.
Bookey-Bassett, S. +4 more
core +1 more source
Safer recruitment? protecting children, improving practice in residential child care [PDF]
, 2007 In the wake of a number of high-profile cases of the abuse of children and young people in residential child care, there have been repeated calls for the improvement of recruitment and selection of residential child care staff.
Stevens, Irene +7 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
INSTITUTION CARE FOR THE FEEBLE-MINDED [PDF]
The Journal of Nervous and Mental Disease, 1889 n ...
openaire +1 more source
Academic Medicine, 1984 The health care system in the United States has been altered by recent economic and political events, including a major recession and a retrenchment in federal nonentitlement spending programs. The economic recovery and the continuing high federal deficits prompt new questions about both the future expansion and the distribution of health spending ...
K W, Tyson, J C, Merrill
openaire +3 more sources
Yaşlı Sorunları Araştırma DergisiOld age is a concept that defines the later periods of life span and the changes that individuals undergo in this period. As the individual, who changes and transforms with his/her environment, grows older, some social problems arise in his/her life. The
İlknur Çetinkaya , Ali Fuat Ersoy
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source