Results 101 to 110 of about 3,551,588 (309)
Journal of Medical Science, 2017 Introduction. Due to the prolonged average life span and constantly increasing number of the elderly, research of this population’s quality of life (QoL) is being conducted to assess the spheres requiring improvement. Aim. To assess and compare the life
Magdalena Pawlaczyk +6 more
doaj +1 more source
Designing with Care - Interior Design and Residential Child Care Final Report [PDF]
, 2006 This exploratory study examined the attitudes to a range of design interventions in four residential care homes for children in South Lanarkshire. The project set out to identify the benefits and disadvantages to young people and staff of a change in ...
Docherty, Catherine +3 more
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Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Motriz: Revista de Educacao FisicaThis study investigates the construct validity of the Spanish version of the CHAMPS questionnaire with institutionalized older adults between the ages of 74 and 90.
José M. Cancela +3 more
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
The contribution of post-accession Polish migrants to adult social care services [PDF]
, 2011 In an increasingly globalised world, for many people who are using the UK adult social care services, interaction with post accession migrants as paid carers now represents an everyday encounter.
Judd, Dawn Beatrice
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Titanium Implants – A Comparison of a Swedish and an Ohio Firm [PDF]
Two firms in the health care market are studied in a case study of the introduction of two almost identical innovations. The two firms, both in the titanium implant business have been chosen so that they match when it comes to origin, technology and ...
Fridh, Ann-Charlotte
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source