Results 61 to 70 of about 17,418,047 (311)

The effect of political leaders on economic growth through institutional change

open access: yesRomanian Economic Journal, 2015
The article summarizes the influence of political leaders on institutions which, according to institutional economics, directly influences economic growth.
Dóra Zolcsák
doaj  

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Une lecture mésoéconomique d’écosystèmes coopératifs, comme leviers d'innovation sociale et de changement institutionnel

open access: yesRevue Interventions Économiques
From a historical and contemporary perspective, this article analyses the process of social innovation towards institutional change produced by cooperative ecosystems: these regroupings of cooperatives that organise themselves collectively in a ...
Justine Ballon, Sylvain Celle
doaj   +1 more source

Resilience revisited: taking institutional theory seriously

open access: yesEcology and Society, 2015
Resilience thinking has in recent decades emerged as a key perspective within research and policy focusing on sustainable development and the global environmental challenges of today.
Martin Sjöstedt
doaj   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Contextualising the context in policy entrepreneurship and institutional change

open access: yes, 2017
While there is a considerable literature concerning policy entrepreneurship and institutional isomorphism, significantly less literature has emerged addressing the impact of context on policy and institutional entrepreneurship and of the interactions ...
Caner Bakir, D. Jarvis
semanticscholar   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Preference formation and institutional change

open access: yesBrazilian Political Science Review, 2009
This essay critically analyses how historical institutionalists and rational choice scholars study institutional stability and change. Special attention is paid to the thorny issued of how political actors’ preferences are formed, with historical ...
Sérgio Praça
doaj  

Исторический контекст тезиса «у нас нет литературы»

open access: yesRusycystyczne Studia Literaturoznawcze, 2019
The article is devoted to modern reconfigurations of the literary process and literature (as a kind of art), experienced in literary criticism as the decline of literature (the thesis “we have no literature” as a statement of the degradation of an art ...
Marina Zagidullina
doaj   +1 more source

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